Results 91 to 100 of about 1,393,311 (289)
Default Bayesian model determination methods for generalised linear mixed models
, 2010 In this paper, we consider a default strategy for fully Bayesian model determination for GLMMs. We address the two key issues of default prior specification and computation.
Overstall, Anthony M. +4 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
PLoS ONE, 2013 X-ray computed tomography (CT) iterative image reconstruction from sparse-view projection data has been an important research topic for radiation reduction in clinic.
Jing Huang +8 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Moment Priors for Bayesian Model Choice with Applications to Directed Acyclic Graphs [PDF]
We propose a new method for the objective comparison of two nested models based on non-local priors. More specifically, starting with a default prior under each of the two models, we construct a moment prior under the larger model, and then use the ...
Luca La Rocca, Guido Consonni
core
Objective and Subjective Rationality in a Multiple Prior Model [PDF]
, 2018 A decision maker is characterized by two binary relations. The first reflects decisions that are rational in an “objective” sense: the decision maker can convince others that she is right in making them.
Marinacciand, Massimo +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Bayesian model comparison based on expected posterior priors for discrete decomposable graphical models [PDF]
The implementation of the Bayesian paradigm to model comparison can be problematic. In particular, prior distributions on the parameter space of each candidate model require special care.
Guido Consonni, Monia Lupparelli
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Objective and Subjective Rationality in a Multiple Prior Model [PDF]
A decision maker is characterized by two binary relations. The first reflects decisions that are rational in an “objective” sense: the decision maker can convince others that she is right in making them.
Itzhak Gilboa +3 more
core