Results 151 to 160 of about 1,393,311 (289)
Multi-Objective Query Optimization for Mobile-Cloud Database Environments Based on a Weighted Sum Model [PDF]
, 2016 In mobile-cloud database environments, users request services executed on a cloud through mobile devices. Requested data might be partially cached on the mobile device itself or must be processed on the cloud which leads to multiple contradicting cost ...
Helff, Florian
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Creative adventures and flow in art-making: A qualitative study of women living with cancer
, 2006 (Introduction) A diagnosis of cancer is recognised as highly fear-arousing. People not only face the discomforts of potentially disfiguring medical treatment but also confront issues of mortality.
Prior, S, Reynolds, F
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Enhance the 3D Object Detection With 2D Prior
IEEE AccessIn the modern field of multi-view 3D detection, interest has seen a notable rise. Existing methods are predominantly focused on constructing dense BEV (Bird’s Eye View) features or utilizing sparse queries for detection. In this paper, we synergize the methodologies of sparse queries with dense BEV feature representation and integrate robust 2D ...
openaire +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Objective prior for the number of degrees of freedom of a t distribution. [PDF]
In this paper, we construct an objective prior for the degrees of freedom of a t distribution, when the parameter is taken to be discrete. This parameter is typically problematic to estimate and a problem in objective Bayesian inference since improper ...
Walker SG, Villa C
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
ObjectFusion: Accurate object-level SLAM with neural object priors
Graphical Models, 2022 Zi-Xin Zou +3 more
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source