Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Efficient preparation of size-controlled sodium alginate microspheres <i>via</i> adaptive Bayesian optimization of the spray process. [PDF]
Feng S, Liu J, Li Z, Tao S.
europepmc +1 more source
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Nivolumab plus ipilimumab and cobimetinib in previously treated microsatellite-stable/DNA mismatch repair-proficient metastatic colorectal cancer: the phase II CheckMate 142 trial. [PDF]
Overman MJ +6 more
europepmc +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Augmented Reality in Surgical Training: Systematic Review of Its Impact on Technical Performance in Surgical Trainees. [PDF]
El Ashry M +4 more
europepmc +1 more source
Objective verification of continuous speech sound discrimination using the acoustic change complex. [PDF]
Jeon EK, Klemuk SA, Brown CJ.
europepmc +1 more source
The Dynamic Relationship Between Objective and Subjective Housing Affordability and Mental Health. [PDF]
Kim G, Kim DY, Seo BK.
europepmc +1 more source
Dendritic Cell Served as Salvage Therapy for Advanced Hepatocellular Carcinoma Resistant to Tyrosine Kinase or Immune Checkpoint Inhibitors. [PDF]
Lee WC +10 more
europepmc +1 more source

