Results 101 to 110 of about 370,221 (305)

Correlations of objective structured clinical examination scores and medical residency evaluations [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective To identify the correlation of medical residency evaluations and Objective structured clinical examination (OSCE) scores. Methods In 2015, 53 participants for standardized medical residency training at Peking Union Medical College Hospital ...
FAN Jun-ping, ZHOU Jing-ya, QIN Ling, ZHANG Sheng-yu, YE Wei, PAN Hui, LI Hang
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An Objective Structured Clinical Examination to Assess Pharmacy Resident Performance

open access: yesINNOVATIONS in Pharmacy, 2017
Objective: The objective was to utilize an Objective Structured Clinical Examination (OSCE) for assessment of pharmacy residents. Innovation: Post-graduate year 1 (PGY1) and post-graduate year 2 (PGY2) pharmacy residents completing multiple, local ...
Kimberly A.B. Cauthon   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Objective structured clinical examination for teaching and assessment: Evidence-based critique

open access: yesClinical Epidemiology and Global Health, 2023
Pooja Dewan   +2 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Prescription Writing Ability of Young Doctors and Medical Interns in Kurdistan Province Iran [PDF]

open access: yesStrides in Development of Medical Education, 2013
Background & Objective: Evaluation of prescriptions of doctors and particularly medical interns is an essential method for obtaining information about prescribing patterns and drug consumption The present study aimed to assess the ability of prescription
Kayumars Rashidi   +2 more
doaj  

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