Results 61 to 70 of about 12,410,556 (249)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Modified Objective Structured Clinical Examination for PL-2 Pediatric Residents

open access: yesMedEdPORTAL, 2015
Introduction This modified objective structured clinical exam (OSCE) is a medical knowledge assessment tool for pediatric residency training programs which can easily be implemented without the need for a simulation center, ancillary staff, or the use of
Michelle Thompson   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Development and evaluation of a simulation-based transition to clerkship course

open access: yesPerspectives on Medical Education, 2020
Background Transition to clerkship courses bridge the curricular gap between preclinical and clinical medical education. However, despite the use of simulation-based teaching techniques in other aspects of medical training, these techniques have not been
Jared P. Austin   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Critical Synthesis Package: Neurology Clerkship Objective Structured Clinical Examination

open access: yesMedEdPORTAL, 2014
This Critical Synthesis Package contains: (1) a Critical Analysis of the psychometric properties and application to health sciences education for the Neurology Clerkship OSCE; and (2) a copy of the Neurology Clerkship OSCE instrument and case files ...
Andrea Leep Hunderfund
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Scores for objective structured clinical examination (OSCE), computer-based testing (CBT), and clinical clerkship (CC).

open access: yes, 2020
Scores for objective structured clinical examination (OSCE), computer-based testing (CBT), and clinical clerkship (CC).
Takashi Nakano (253277)   +3 more
core   +1 more source

Objective structured clinical examination in physiotherapy teaching: a systematic review [PDF]

open access: yes, 2019
Introduction: Problems related to the clinical abilities of physiotherapy students are not always identified throughout the educational process and might only be observed when these future professionals have to treat patients.
Aline Moreira Ribeiro (4957915)   +2 more
core   +2 more sources

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