Results 111 to 120 of about 23,660,772 (290)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Assessment of metropolitan livability variations using objective-subjective approach
World Development SustainabilityA case of the rapid propensity of urbanization leading to skewed dynamics of metropolitan urban agglomeration (MUA) and its extent of complementarities with the socio-economic and socio-cultural well-being of the communities. Analyses of the dynamics and
Arpan Paul
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Statistical perspectives on health and well-being
, 2016 model based approach for ordinal data in health ...
capecchi, stefania
core
Scientific ReportsObjective structured clinical examination (OSCE) is a valid method to evaluate medical students’ competencies. The present cross-sectional study aimed at determining how students’ coping and health-related behaviors are associated with their ...
Noémie Barret +8 more
doaj +1 more source
BuildingsThis review investigates the role of building windows in supporting occupant well-being through access to natural views and daylight. This review synthesizes recent interdisciplinary research from environmental psychology, building science, and human ...
Siqi He, Wenli Zhang, Yang Guan
doaj +1 more source
Does Objective Well-Being Cause Subjective Well-Being? (1998-2012 Albanian Voter Analyze)
Mediterranean Journal of Social Sciences, 2013 This paper presents an overview of the correlation and changing dynamics of the main determinant indicators of economic welfare (GDP per capita, Inflation, Employment/Unemployment, Total Government Revenue, Total Investment, GNI per capita) and subjective welfare indicators (Subjective Welfare Indicator as defined by R.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source