Results 131 to 140 of about 1,517,059 (245)

Pet Co-Sleeping and Well-Being: Evidence from Two Cross-Sectional Online Surveys of Youths and Adults. [PDF]

Clocks Sleep
Endo K, Shimatani K, Suzuki N.
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exam Scheduling Preferences and Their Impact on Student Well-Being and Performance: A Call for Objective Evaluation and Supportive Interventions [Letter]

Advances in Medical Education and Practice
Talal El-Jabri, Obaid Rahman, Ameer Hamid A Khan Addenbrooke’s Hospital, Cambridge University Hospitals NHS Trust, Cambridge, UKCorrespondence: Talal El-Jabri, Cambridge University Hospitals NHS Trust, Cambridge, UK, Email talal.el-jabri1@nhs ...
El-Jabri T, Rahman O, Khan AHA
doaj  

Individual differences in affect: explaining work environment perceptions and later wellbeing. [PDF]

Sci Rep
Craven LH, Kajonius PJ.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Health and well-being of mothers and co-parents during the first 12 months post partum: study protocol of the national SOCRATES cohort study in Switzerland. [PDF]

BMJ Open
Gaucher L, Desplanches T, Sormani J, Cattani G, Mueller AN, Celetta E, Widmer IN, Lorthe E, Grylka-Baeschlin S.   +8 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Real-World Effectiveness Versus Efficacy in a Study Environment: How Smartphones Help Capture Meaningful Patient Recovery Trajectories - A Commentary on "Physical Performance Continues to Improve After Surgery for Sciatica, Exceeding Recovery Periods of Physical Capacity and Patient-Reported Outcomes: Multicenter Prospective Observational Study". [PDF]

Neurospine
Staartjes VE.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source