Results 161 to 170 of about 23,660,772 (290)

Knowledge, Tennis, and Objective List Accounts of Well-Being

open access: yesPhilosophia
Abstract This paper argues that objective list accounts of well-being cannot account for the fact that not all knowledge, an item typically on such lists, is good for people independently of their attitudes toward it. The most obvious way to distinguish that knowledge that is intrinsically valuable is precisely in terms of subjective ...
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The Anatomy of Subjective Well-Being [PDF]

open access: yes
Subjective Well-Being has increasingly been studied by several economists. This paper fits in that literature but takes into account that there are different aspects of life such as health, financial situation, and job. We call them domains.
P. Frijters   +2 more
core  

The Impact of Individual Capabilities on Ecosystem Services and Farmers’ Well-Being: A Case Study of the Loess Plateau, China

open access: yes
Exploring the impact of individual capabilities on ecosystem services and farmers’ well-being is conducive to discovering the complex relationship between ESs and human well-being, and has clear practical value for the sustainable management and ...
Yayan Lu   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spiritual Well-being in Cancer Patients who Undergo Chemotherapy [PDF]

open access: yes
Objective: Spiritual well-being harmonizes several dimensions of human's life and is essential for coping with diseases. Chronic illnesses such as cancer cause crisis in physical, psychological and spiritual dimensions of ones life.
حبیبی, عقیل   +1 more
core  

Psychology of Well-being. Theory, Research and Practice

open access: yes, 2011
Psychology of Well-Being: Theory, Research and Practice is a peer-reviewed devoted to understanding the biopsychosocial and behavioural factors leading to enhanced well-being, optimal emotional processing and the prevention of psychological dysfunction ...
RUINI, CHIARA
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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