Results 51 to 60 of about 188,471 (314)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
We theoretically develop and empirically validate a measure of mindset of obligation, building on the concept of the form of commitment that receives the least attention from scholars – normative commitment.
Rubino, C +7 more
core +1 more source
Formation of lease agreement in pre-classical Roman law
Modern civil law is characterized by the emergence of undefined and mixed types of contracts. This development necessitates the identification of specific features that can help to classify contracts for legal certainty.
Mikhail M. Pestov
doaj +1 more source
The Responsibility of a Service Provider in Classical Roman Law
The article is devoted to the responsibility of a service provider in Classical roman law. The author describes the main social and legal factores led to the changes in a service agreement in comparing with its structure in Preclassical period of roman ...
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Is the Duty to Prevent Genocide an Obligation of Result or an Obligation of Conduct according to the ICJ? (blogpost) [PDF]
This post analyses the duty to prevent genocide embodied in the 1948 UN Genocide Convention as described by the International Court of Justice in the Bosnia v. Serbia case.
Longobardo, M.
core
Dogma, or the deep rootedness of obligation
This chapter seeks to make sense of the 'break' in terms of the primacy of obligation as rooted in the 'dogmatic', in the way that Alain Supiot has developed it; and shows that argument alongside the ideal of rootedness, more accurately that of 'taking ...
Christodoulidis, Emilios
core +1 more source
Hanefî-Mâtürîdî Kelâm Okulunda Aklî Teklif
İslam düşüncesinde teklif konusunun farklı mezhepler tarafından vahiy ve akıl ekseninde değerlendirilmesi, bağımsız insan varlığının ilahi sorumluluğunun kaynağıyla ilgili problemlere çözüm bulmaya yönelik bir faaliyettir.
Yunus Eraslan
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

