Results 71 to 80 of about 1,519,165 (389)
Obligation, Permission, and Bayesian Orgulity [PDF]
This essay has two aims. The first is to correct an increasingly popular way of misunderstanding Belot's Orgulity Argument. The Orgulity Argument charges Bayesianism with defect as a normative epistemology.
Nielsen, Michael, Stewart, Rush T.
core
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Higher Education: Obligation or Opportunity? [PDF]
From the beginning of my experience at Marquette, I continually observed students that appeared to demonstrate no enthusiasm for getting an education, reflected in a noticeable lack of participation in class discussions.
Knowles, Megan
core +1 more source
Extraterritorial Obligations and the Obligation to Protect
Since the late 1970s, what we today label ‘globalisation’ has altered many aspects of international law, not least international human rights law. This has been reflected inter alia in increased calls for universal respect for human rights beyond a state’s territorial border.
openaire +3 more sources
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The Obligation to Participate in Biomedical Research [PDF]
The current prevailing view is that participation in biomedical research is above and beyond the call of duty. While some commentators have offered reasons against this, we propose a novel public goods argument for an obligation
Emanuel, Ezekiel J.+2 more
core +1 more source
Loyalty in Civil-Law Relationships as Found in the Polish Law
This paper discusses manifestations of loyalty as found in selected civil-law regulations, as well as the possible consequences of disloyalty, either during negotiations or for the duration of the obligation relationship, and as exemplified by Actio ...
Ewa Lewandowska
doaj +1 more source
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Imperative change and obligation to do [PDF]
The ambition of the paper is to provide a solution to the problem posed by Von Wright (1999): how is it possible that the two actions, one of producing P and the other of preventing P can have different deontic status, the former being obligatory and the
Žarnić, Berislav
core
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source