Results 91 to 100 of about 250,819 (249)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2012 Report is an evaluation of the engagement process used in 'SDC Supplier Obligation project : household energy from 2011 : final report'.Publisher ...
Smith, Steve, Icarus Collective
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
LEGAL ISSUES OF LIABILITY OF HOMEOWNERS
Гуманитарные и юридические исследования, 2021 Activities of such a modern civil legal form of apartment building management, as association of homeowners has not only advantages, but also involves liability according to the legislation of the Russian Federation.
Vera Grigorievna Fedorova +1 more
doaj
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The principle of fairness : theory, defence, and application [PDF]
Theories of social justice propose various principles for the just regulation of social institutions and practices. However, why should individuals comply with the rules of just social institutions?
Kim, Dong-il
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Perspectives in Clinical ResearchRandomized controlled trials (RCTs) are considered gold standard study designs. With increasing knowledge and experience, the requirements for designing, conduct and reporting of RCTs is becoming more demanding.
Jennee Moirangthem +2 more
doaj +1 more source
Treaty obligation to promote public education and the teaching of international law
, 2007 Currently various international treaties require contracting States to disseminate the text of international conventions and to promote public education concerning relevant issues of international law.
Tanaka, Y.
core +1 more source