Results 91 to 100 of about 552,453 (312)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
German Law JournalThe story of national judges’ participation in the process of dialogue with the Court of Justice of the European Union (ECJ) pursuant to Article 267 TFEU is a well-known one.
Urszula Jaremba, Marleen Kappé
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Public Justification and the Reactive Attitudes [PDF]
, 2018 A distinctive position in contemporary political philosophy is occupied by those who defend the principle of public justification. This principle states that the moral or political rules that govern our common life must be in some sense justifiable to ...
Taylor, Anthony
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 1987 本研究は歯周病の臨床検査として偏性嫌気性スピロヘータを含めた歯肉縁下プラークの細菌叢を検索する方法を確立するという目的で行った。被験者28名において歯周ポケット内細菌叢を検索し各培地・培養法の比較, 検討を行った。非選択培地としてはスチールウールジャー法を用いたEG寒天培地が適していることが分かった。また偏性嫌気性スピロヘータの培養については, プレートインボトル法を用いた10%Rumen液入りMedium10培地が優れているということが示された。以上の2つの培地に10種類の選択培地を加え患者と健常者について歯周ボケット内の細菌叢の検索を行ったが, 特にスピロヘータは半数以上の患者において総菌数の10%以上培養によって検出され, これは位相差顕微鏡の鏡検におけるスピロヘータの割合と同様の値になった ...
openaire +3 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
How to Preach Jesus Christ in The Era of The New Evangelization? [PDF]
, 2014 The main task of the Church is to reach out to man with a message of God who saves an individual through Jesus in the Holy Spirit. If preaching the eternal Word – Jesus is the primary obligation of the Church to man and man is able to open himself to ...
Śmigiel, Wiesław
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
ECTHR’S PERSPECTIVE ON THE REFUSAL OF A DOMESTIC COURT TO MAKE A PRELIMINARY REFERENCE TO THE CJEU [PDF]
Challenges of the Knowledge SocietyNowadays, even if the EU is not yet a party to the ECHR and its acts cannot be subject of applications to the Strasbourg Court, issues relating to EU law have been raised regularly with the Strasbourg Court. Art. 6 para.
Laura-Cristiana SPĂTARU-NEGURĂ
doaj