Results 171 to 180 of about 4,109,796 (295)

Intravenous thrombolysis in acute ischemic stroke after recent direct oral anticoagulant intake: toward evidence-informed care. [PDF]

Front Neurol
Zupan M, Šabovič M, Kermer P, Frol S.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Good practice in observational epidemiological research: guidelines for biostatisticians on Ethics Committees

, 2008
SISMEC Working group on Observational Studies, VESTRI, Anna Rita   +1 more
core  

Ischemic stroke in Peru: a scoping review of trends, outcomes, and evidence gaps. [PDF]

Front Epidemiol
Alarcon-Ruiz CA, Gutierrez-Arratia J, Concha-Querevalú L, Barrientos-Ventura E, Moreno-Arias J, Otiniano-Sifuentes R, Ecos R, Zunt JR, Miranda JJ.   +8 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

From fragmentation to federation: multi-partner OMOP implementation in Uganda enabling global real-world evidence generation. [PDF]

Front Digit Health
Kanyike F, Nanungi A, Dickinson H, Adam A, Brash J, Do T, Otike C, Bogart M, Asiimwe A, Zandt MV, Mutuluuza CK.   +10 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Right supraclavicular fossa ultrasound view for real-time central venous catheter tip positioning in adult patients: A systematic review. [PDF]

Indian J Anaesth
Maurya I, Maurya RG, Lohiya A, Daniel RA, Mohta A, Saraswat S.   +5 more
europepmc   +1 more source

Methodologic issues regarding background mortality in observational studies [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2011
Osnabrugge, Ruben, Head, Stuart, Kappetein, Arie-Pieter   +2 more
openaire   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source