A Methodological Approach to Adjust for Channeling Bias in Nonrandomized Observational Studies: Application to Cyclooxygenase-2 (COX-2) Specific Inhibitors [PDF]
Dan Pettitt +4 more
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
The gut microbiota-brain-CAR T cell axis: a systematic review of gut microbiome modulation and its impact on neurological complications and treatment responses in CAR T cell therapy. [PDF]
Pillai AA +8 more
europepmc +1 more source
OBSERVE Horizon Scanning Methodology Report
The Report will document the four Horizon scanning approaches in detail, discuss the experiences and elaborate lessons learned and recommendations for optimization.
openaire +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Bridging research and practice: a pilot trial of an adapted social skills program for autism in public services. [PDF]
Mairena MA +11 more
europepmc +1 more source
Neural network-based estimates of Southern Ocean net community production from in situ O 2 / Ar and satellite observation: a methodological study [PDF]
Chueh‐Hsin Chang +2 more
openalex +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
A comprehensive analysis of oxytocin: a potential brain-based treatment to regulate obesity. [PDF]
Alsayegh AA +7 more
europepmc +1 more source

