Results 121 to 130 of about 65,758,577 (259)

Self-Selection Bias in Randomized and Observational Studies on Screening Mammography: A Quantitative Assessment [PDF]

Philippe Autier International Prevention Research Institute (IPRI), Lyon, 69002, FranceCorrespondence: Philippe Autier, International Prevention Research Institute (iPRI), Lyon, 69002, France, Email Philippe.autier@i-pri.orgBackground: Observational ...
Autier P
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A comparison of two methods of estimating propensity scores after multiple imputation

, 2011
In many observational studies, analysts estimate treatment effects using propensity scores, e.g., by matching or sub classifying on the scores. When some values of the covariates are missing, analysts can use multiple imputation to fill in the missing ...
Reiter, Jerome P., Mitra, Robin, Mitra, R., Reiter, Jerome P, Reiter, J.P.   +4 more
core   +1 more source

Navigating through archives, libraries and museums: Topic Maps as a harmonizing instrument [PDF]

, 2005
The paper deals with the possibility of creating a topic map based system where different sectors of cultural heritage would interact with users, by monitoring the navigation histories of users and the statistics on the searches, in order to authorize ...
Vassallo, Salvatore
core   +1 more source

Dietary Interventions in Parkinson’s Disease

Journal of Parkinson’s Disease
Several dietary patterns and nutritional supplements have been linked to the development, progression, and symptomatic treatment of Parkinson’s disease (PD).
Indy van der Berg, Sabine Schootemeijer, Karin Overbeek, Bastiaan R. Bloem, Nienke M. de Vries   +4 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Diet patterns associated with cognitive decline: methods to harmonize data from European and US cohort studies

Frontiers in Nutrition
The impact of dietary intake on cognitive outcomes and dementia prevention is a topic of increasing interest. Meta-analyses of observational studies, mostly conducted within US and European populations, have reported benefits of healthy diet patterns on ...
Amaia Ayala-Garcia, Natalia Soldevila-Domenech, So-Yun Yi, Rafael de la Torre, Rafael de la Torre, Rafael de la Torre, Lyn M. Steffen, for the IAFNS Retrospective Harmonization Expert Working Group, Courtney K. Blackwell, Christina Khoo, Maxwell Armand Mansolf, Emilio Ros, Linda Snetselaar, Tina Wey   +13 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies.

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies.
Ana Clara Nunes Soares (18264632), Emilly Cássia Soares Furtado (18264617), Rayana Carvalho Barros (18264635), Rayanne Mesquita Bendelack (18264623), Pablo Fabiano Moura das Neves (18264629), Lorena Jarid Freire De Araújo (18264620), Cibele Nazaré Câmara Rodrigues (8682969), Erica Feio Carneiro Nunes (8303637), Bianca Callegari (2575204), Elizabeth Alves Gonçalves Ferreira (12816446), Nazete dos Santos Araujo (18264626), João Simão de Melo-Neto (12936294), Natália de Souza Duarte (18264611), Tainah Lacerda Santos (18264638), Yury Souza De Azevedo (18264614)   +14 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source