Results 111 to 120 of about 450,753 (263)
Global Spine JournalStudy design This study constitutes a systematic review of the literature. Objective The aim of this study was to identify and present all available studies that report on the costs of osteobiologics used in anterior cervical discectomy and fusion (ACDF).
Andreas K. Demetriades +6 more
doaj +1 more source
Pulmonary Artery Hypertension in Ankylosing Spondylitis: A Review
Juvenis ScientiaPulmonary arterial hypertension (PAH) is a serious complication that can occur in patients with connective tissue diseases, such as ankylosing spondylitis (AS).
Carvalho, J.F. +4 more
doaj +1 more source
Vitamin D Receptor Activators and Clinical Outcomes in Chronic Kidney Disease
International Journal of Nephrology, 2011 Vitamin D deficiency appears to be an underestimated risk factor for cardiovascular disease in patients with chronic kidney disease. Evidence from both basic science and clinical studies supports the possible protective role of vitamin D beyond its ...
Luciana Gravellone +5 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Voting contagion: Modeling and analysis of a century of U.S. presidential elections.
PLoS ONE, 2017 Social influence plays an important role in human behavior and decisions. Sources of influence can be divided as external, which are independent of social context, or as originating from peers, such as family and friends.
Dan Braha, Marcus A M de Aguiar
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Perioperative glycemic control in patients undergoing cardiac surgery
Polish Journal of Thoracic and Cardiovascular SurgeryDiabetes mellitus (DM) is one of the most common chronic diseases, affecting globally about 537 million adults. Cardiovascular disease remains the leading cause of death and medical emergencies in the DM patient population.
Dariusz Bednarski, Łukasz Krzych
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source