Results 21 to 30 of about 65,758,577 (259)

How Dietary Factors Affect DNA Methylation: Lesson from Epidemiological Studies

Medicina, 2020
Over the past decades, DNA methylation has been proposed as a molecular mechanism underlying the positive or negative effects of diet on human health.
Andrea Maugeri, Martina Barchitta
doaj   +1 more source

Burnout Syndrome prevalence of on-call surgeons in a trauma reference hospital and its correlation with weekly workload: cross-sectional study

Revista do Colégio Brasileiro de Cirurgiões
Objective: to determine the prevalence of Burnout Syndrome (BS) for surgeons working in referral hospital for trauma in Maceio and to evaluate the possible correlation between BS and weekly workload.
RODRIGO NOBRE DE NOVAIS, LOUISE MATOS ROCHA, RAISSA JARDELINO ELOI, LUCIANO MENEZES DOS SANTOS, MARINA VIEGAS MOURA REZENDE RIBEIRO, FERNANDO WAGNER DA SILVA RAMOS, FERNANDO JOSÉ CAMELLO DE LIMA, CÉLIO FERNANDO DE SOUSA-RODRIGUES, FABIANO TIMBÓ BARBOSA   +8 more
doaj   +1 more source

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies [PDF]

, 2002
BACKGROUND: The age-specific relevance of blood pressure to cause-specific mortality is best assessed by collaborative meta-analysis of individual participant data from the separate prospective studies.
Prospective Studies Collaboration Team, Lewington, Sarah, Peto, Richard, Jamrozik, Konrad D., Prospective Studies Collaboration, Clarke, Robert, Qizilbash, Nawab, Collins, Rory, Lissner, Lauren,   +8 more
core   +1 more source

Hyperoxia in critically ill patients with sepsis and septic shock: a systematic review

Journal of Anesthesia, Analgesia and Critical Care, 2023
Background In septic patients, hyperoxia may help with its bactericidal effects, but it may cause systemic impairments. The role of hyperoxia and the appropriate oxygen target in these patients is unknown.
Francesca Romana Catalanotto, Mariachiara Ippolito, Alice Mirasola, Giulia Catalisano, Marta Milazzo, Antonino Giarratano, Andrea Cortegiani   +6 more
doaj   +1 more source

Multi-Center Healthcare Data Quality Measurement Model and Assessment Using OMOP CDM

Applied Sciences, 2021
Healthcare data has economic value and is evaluated as such. Therefore, it attracted global attention from observational and clinical studies alike. Recently, the importance of data quality research emerged in healthcare data research.
Ki-Hoon Kim, Wona Choi, Soo-Jeong Ko, Dong-Jin Chang, Yeon-Woog Chung, Se-Hyun Chang, Jae-Kwon Kim, Dai-Jin Kim, In-Young Choi   +8 more
doaj   +1 more source

Good practice in observational epidemiological research: guidelines for biostatisticians on Ethics Committees

, 2008
The problem of defining and approving observational studies has attracted growing attention in the clinical and epidemiological research sector since the Italian Ministry of Health’s publication, on 2 September 2002, of its circular n.6 on the work of ...
Bamfi F., Decarli A., ACCORDINI, Simone, Gregori D., Galassi G., Merletti F., Zucchetto M., SISMEC Working Group on Observational Studies, DE MARCO, Roberto, Carle F., Sotgiu G., Grigoletto F., Marinoni A., Vestri A., Volpato S., Baussano I., Patarnello F., Villani S., Simoni L., Serio G., Montomoli C., Frigo A. C., Stendardo A.   +22 more
core   +2 more sources

Methodologies for generating and evaluating clinical and performance evidence for high-risk and innovative medical devices and in vitro diagnostics: a scoping review

Frontiers in Medical Technology
IntroductionHigh-risk and innovative medical devices (MDs) and in vitro diagnostic devices (IVDs) in the European Union are subject to increasingly stringent and evolving regulatory requirements.
Nensi Bralić, Ružica Bandić, Miro Vuković, Danira Matijaca, Renata Valsami, Panagiotis Zoumpoulakis, Kalle Schnitzer, Mari Levula, Risto Roine, Antti Viitala, Antti Pihlava, Olivia McDermott, Ana Marušić   +12 more
doaj   +1 more source

topicmodels: An R Package for Fitting Topic Models [PDF]

, 2011
Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent ...
Kurt Hornik, Hornik, Kurt, Grün, Bettina, Bettina Grun   +3 more
core   +1 more source

Dietary inflammatory index and non-alcoholic fatty liver disease risk: a systematic review and meta-analysis of observational studies

Frontiers in Nutrition
AimChronic inflammation plays a significant role in the progression of non-alcoholic fatty liver disease (NAFLD). Adopting an anti-inflammatory diet can help prevent or mitigate NAFLD and its associated complications.
Bahareh Amirkalali, Mohammad Farahmand, Minoo Hasan Rashedi, Ali Gholami, Ali Gholami, Fateme Sheikholmolooki, Mohadeseh Sedighi, Mohadeseh Sedighi, Azam Doustmohammadian   +8 more
doaj   +1 more source

The obesity conundrum in sepsis

BMC Anesthesiology, 2017
While the long-term negative effects of obesity on health is a well-studied phenomenon, its effects on acute illnesses seem to be the contrary. Several studies have indicated the possibility of an ‘obesity paradox’ in sepsis – where overweight and obese ...
Pauline Yeung Ng, Matthias Eikermann
doaj   +1 more source