Results 161 to 170 of about 2,471,157 (341)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Pregnancy Outcomes after Treatment for Cervical Cancer Precursor Lesions: An Observational Study

, 2017
Sheila Weinmann, Allison L. Naleway, Geeta K. Swamy, Girishanthy Krishnarajah, Bhakti Arondekar, Jovelle Fernandez, Evan R. Myers   +6 more
openalex   +2 more sources

The safety of upper gastrointestinal endoscopic biopsy in patients receiving antithrombic drugs. A single-centre prospective observational study [PDF]

, 2019
Hilmi Bozkurt, Tolga Ölmez, Can İbrahim Bulut, Özlem Zeliha Sert, Zehra Zeynep Keklikkıran, Erdal Karaköse, Aziz Serkan Senger, Sabiye Akbulut, Erdal Polat, Mustafa Duman   +9 more
openalex   +1 more source

Idiopathic pulmonary fibrosis and intestinal disorders: An observational study

, 2022
Caramaschi Stefania, A. Bertani, Stefania Cerri, Colecchia Antonio, Ambrosini-Spaltro Andrea, Gianrocco Manco, Tiziana Salviato, Luca Reggiani Bonetti   +7 more
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Tobacco Quitline Engagement and Outcomes among Primary Care Patients Reporting use of Tobacco or Dual Tobacco and Cannabis: An Observational Study [PDF]

, 2020
Jennifer B. McClure, Gwen T. Lapham
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Temperature Monitoring in Prehospital Emergency Medical Vehicles - An Observational Study. [PDF]

Prehosp Disaster Med
Maait Y, Phillipson L.
europepmc   +1 more source

Earlier Physical Therapy Input Is Associated With a Reduced Length of Hospital Stay and Reduced Care Needs on Discharge in Frail Older Inpatients: An Observational Study

, 2017
Peter Hartley, Victoria L. Keevil, Ledia Alushi, Rebecca L. Charles, Eimear Conroy, Patricia M. Costello, Becki Dixon, Aida M. Dolinska-Grzybek, Diana Vajda, Román Romero‐Ortuño   +9 more
openalex   +1 more source

Undertaking the surgical count: An observational study

, 2021
Victoria Ruth Warwick, Brigid M. Gillespie, Anne McMurray, Karen G Clark-Burg   +3 more
openalex   +2 more sources