Results 141 to 150 of about 1,473,678 (357)

Suboptimal Health Status and Stress: An Observational Study on Medical Students in Islamabad, Pakistan

open access: yesLife and Science
Objective: This study was conducted to find the frequency of suboptimal health and its association with perceived stress levels among medical students at a private university medical college in Islamabad, Pakistan.
Maryam Iqbal   +8 more
doaj   +1 more source

An observational study of community health care nurses’ knowledge about delirium

open access: yes, 2017
Rachid Akrour,1 Henk Verloo2 1Department of Geriatric Rehabilitation, Lausanne University Hospital, Lausanne, 2Department of Nursing Sciences, University of Applied Sciences and Arts Western Switzerland, Sion, Switzerland Background: Early detection of ...
Akrour R, Verloo H
core  

A Multicentre Observational Study of HIV, TB and Risk of Chronic Lung Disease in Urban West Africa

open access: green, 2022
Douglas Fink   +16 more
openalex   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Real-World Biologic Use Patterns in Severe Asthma, 2015–2021 : the CLEAR Study

open access: yes
Acknowledgments We thank all members of the CLEAR Study Working Group (full details in eTable 1). We also thank Nasloon Ali, formerly of Observational and Pragmatic Research Institute, Singapore, for their contributions to the design and conduct of the ...
Emmanuel, Benjamin   +17 more
core   +1 more source

EU-WISE: a patient observational study

open access: yes, 2015
EU-WISE is an integrated project under the 7th Framework Programme of the European Commission designed to focus on understanding capabilities, resources, and changes in health related practices in community and cultural context across EUROPE.
Koetsenruijter, J. (Radboudumc)
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Alternative monotherapy or add-on therapy in patients with epilepsy whose seizures do not respond to the first monotherapy: an Italian multicenter prospective observational study.

open access: yes, 2013
A prospective multicenter observational study was undertaken on children and adults with epilepsy in whom first monotherapy failed, to assess indications and effects of alternative monotherapy vs. polytherapy.
Mattana F   +6 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

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