Results 121 to 130 of about 1,473,678 (357)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Trends in detectable viral load by calendar year in the Australian HIV observational database

, 2011
Background Recent papers have suggested that expanded combination antiretroviral treatment (cART) through lower viral load may be a strategy to reduce HIV transmission at a population level.
Cooper, D.A., Roth, Norman, Templeton, D.J., John Chuah, Templeton, David J., Cooper, D., Hamish McManus, Templeton, D., Ian Woolley, Petoumenos, Kathy, Roth, N., McManus, Hamish, Canavan, P., Woolley, I., Petoumenos, K., Law, M.G., David J Templeton, Chuah, John, Peter Canavan, Mulhall, Brian, Canavan, Peter, Roth, Norm, Cooper, David A., Law, Matthew G., McManus, H., Kathy Petoumenos, Australian HIV Observational Database (AHOD).,, David A Cooper, Matthew G Law, Nolan, D., Templeton, David, null null, Law, M., Brian Mulhall, Norm Roth, Mulhall, B., Cooper, David, Woolley, Ian, Chuah, J., Law, Matthew   +39 more
core   +1 more source

Review for "Lower Cardiorenal Risk with Sodium-Glucose Cotransporter-2 Inhibitors versus Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Patients without Cardiovascular and Renal Diseases: A large multinational observational study"

, 2020

openalex   +1 more source

Prospective Observational Study on Pazopanib in Patients Treated for Advanced or Metastatic Renal Cell Carcinoma in Countries in Asia Pacific, North Africa, and Middle East regions: PARACHUTE Study [PDF]

, 2021
Mustafa Erman, Bivas Biswas, Pongwut Danchaivijitr, Lingwu Chen, Yoke Fui Wong, Tarek Hashem, Chun Sen Lim, Bülent Karabulut, Hsiao‐Jen Chung, Chandra Chikatapu, Sara Ingles, Khémaies Slimane, Ravindran Kanesvaran   +12 more
openalex   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Critical illness outcome study: an observational study of protocols and mortality in intensive care units

Open Access Journal of Clinical Trials, 2011
Naeem A Ali1, David Gutteridge2, Sajid Shahul3, William Checkley4, Jonathan Sevransky4, Greg S Martin2 1The Ohio State University Medical Center, Columbus, OH; 2Emory University, Atlanta, GA; 3Beth Israel Deaconess Medical Center, Boston, MA; 4Johns ...
Sevransky J, Checkley W, Shahul S, Gutteridge D, Ali NA, Martin GS   +5 more
doaj  

Constructor-based Observational Logic

, 2003
This paper focuses on the integration of reachability and observability concepts within an algebraic, institution-based framework. In the first part of this work, we develop the essential ingredients that are needed to define the constructorbased ...
Suprieure Cachan, M. Bidoit, R. Hennicker, Observational Logic, Ecole Normale   +4 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Tobacco Price Increase and Smoking Cessation in Japan, a Developed Country With Affordable Tobacco: A National Population-Based Observational Study

Journal of Epidemiology, 2016
Takehiro Tabuchi
doaj   +1 more source

An observational study of acarbose treatment in patients with type 2 diabetes from the Middle East and Morocco

, 2013
Abdul R Shihabi,1 Essam M Moussa,2 Hania Sobierajska,3 Birgit Schmidt4 1Al Ain Centre, Dubai, United Arab Emirates; 2New Jeddah Hospital, Jeddah, Saudi Arabia; 3Etihad Airways Medical Centre, Abu Dhabi, United Arab Emirates; 4Bayer Schering Pharma AG ...
Sobierajska H, Moussa EM, Schmidt B, Shihabi AR   +3 more
core