Results 131 to 140 of about 51,352,550 (334)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
An observational study of pediatric healthcare burden in Angelman syndrome: results from a real-world study. [PDF]
, 2019 BACKGROUND:The objective of this study is to describe variations in the healthcare resource utilization (HRU) among individuals with Angelman syndrome (AS) over the first 12 years of life. Data for this study were drawn from the AS Natural History study (
Bird, Lynne M +4 more
core +1 more source
Journal of the National Cancer Institute, 2019 Background Human papillomavirus vaccination and cervical screening are lacking in most lower resource settings, where approximately 80% of more than 500 000 cancer cases occur annually. Visual inspection of the cervix following acetic acid application is
Liming Hu +18 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Osteoarthritis among elderly: cross-sectional study of hospitalization between 2010 and 2022
Revista Pesquisa em FisioterapiaINTRODUCTION: Osteoarthritis is a common joint disease and one of the main causes of years lived with disabilities as well as one of the reasons for visits to health services.
Aranzazu Cueva-G.Cantón +3 more
doaj +1 more source
Clinical specialty training in UK undergraduate medical schools: A retrospective observational study [PDF]
, 2019 Objectives: To determine if increased exposure to clinical specialties at medical school is associated with increased interest in pursuing that specialty as a career after foundation training. Design: A retrospective observational study.
Alexander, Emma C +5 more
core +1 more source
British medical journal, 2016 Study question What has been the effect on purchases of beverages from stores in Mexico one year after implementation of the excise tax on sugar sweetened beverages?
M. Colchero +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Modality Choice for Generation of Referring Acts: Pointing versus Describing [PDF]
, 2007 The main aim of this paper is to challenge two commonly held assumptions regarding modality selection in the generation of referring acts: the assumption that non-verbal means of referring are secondary to verbal ones, and the assumption that there is a ...
Piwek, Paul
core +1 more source