Results 231 to 240 of about 49,584,610 (301)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Cognitive Impairment in People With Diabetes-Related Foot Ulcers: A Multicentre, Case-Control, Observational Study. [PDF]

Int Wound J
Karunathilaka N, Lazzarini PA, MacAndrew M, Finlayson K, Parker C.   +4 more
europepmc   +1 more source

Immunohistochemical Expression of P16 in Cervical Lesions: An Observational Study. [PDF]

JNMA J Nepal Med Assoc
Ansari SN, Kunwar R, Vaidya SA.
europepmc   +1 more source

Interruptions and multitasking in anaesthesia nursing: a prospective observational study of cognitive strain and workflow patterns. [PDF]

BMJ Open Qual
Hölzing CR, Heilgenthal P, Sellmann F, Meynhardt C, Grundgeiger T, Scheuchenpflug R, Meybohm P, Happel O.   +7 more
europepmc   +1 more source

Therapeutic drug monitoring of adalimumab in hidradenitis suppurativa: a prospective observational study. [PDF]

Front Immunol
Chen SX, Wafae BGO, Look-Why S, Otto T, Snyder C, Sweet W, Ashina N, Gibson R, Salian P, Doroudian Tehrani M, Dervieux T, Kimball AB, Porter ML.   +12 more
europepmc   +1 more source

Electrocardiographic Abnormalities in Patients With Leptospirosis: A Clinical Observational Study. [PDF]

Cureus
Pranav B K, Adalarasan S, S Y, Nikesh P, C H.   +4 more
europepmc   +1 more source