Results 271 to 280 of about 51,352,550 (334)

Restriction Evaluation of Appropriate Carbapenem Therapy (REACT): A Multisite Observational Study. [PDF]

open access: yesJ Pharm Technol
Wells DA   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Respiratory Muscle Strength and Imaging Parameters in Smokers: A Prospective Observational Study. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Matsuo Y   +9 more
europepmc   +1 more source

Spatiotemporal dynamics of leptospirosis in Europe: a retrospective observational study with prospective projections. [PDF]

open access: yesLancet Reg Health Eur
Fanelli A   +13 more
europepmc   +1 more source

Fenfluramine in SCN1A-related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability. [PDF]

open access: yesEpilepsia Open
Dell'Isola GB   +12 more
europepmc   +1 more source

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