Results 211 to 220 of about 1,427,616 (263)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Efficacy and toxicity of neoadjuvant chemotherapy versus chemo-immunotherapy in triple-negative breast cancer patients with and without germline BRCA mutations. [PDF]

Breast Cancer Res Treat
Etan T, Cohen L, Bar Y, Leshem Y, Lerner S, Stepansky I, Shiran I, Sonnenblick A, Shachar SS.   +8 more
europepmc   +1 more source

Survival analysis of time to amputation following diabetic foot ulcer diagnosis among Indonesians. [PDF]

PLoS One
Lianawati, Laohasiriwong W, Htike KM, Thinkhamrop K, Mahato RK.   +4 more
europepmc   +1 more source

Mid- to long-term outcomes and survival of total hip arthroplasty using a Kerboull-type acetabular reinforcement plate: an analysis of associated factors. [PDF]

Arch Orthop Trauma Surg
Gosho S, Kaku N, Hosoyama T, Shibuta Y, Tanaka K.   +4 more
europepmc   +1 more source

Incorporating variation in death times improves predictions of ectotherm responses to stressful temperatures. [PDF]

PLoS Biol
Bullard GW, Buckley LB, Kingsolver JG.
europepmc   +1 more source

Recurrence of Colorectal Cancer After Liver Transplant for Isolated Colorectal Liver Metastases: A Narrative Review. [PDF]

Cancers (Basel)
Agrawal R, Choi AJ.
europepmc   +1 more source

Coarse-Grained Modeling and Interpretation of Phenomenological Creep Rate Behavior with Experimental Validation. [PDF]

Entropy (Basel)
Gong T, Zhou D, Guan X, Du YM.
europepmc   +1 more source

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Maxillary Overdenture Implant Survival Rate and Prosthetic Complications: An Observational Study

Global Academic Journal of Medical Sciences, 2023
Background: Edentulism is a serious public health problem since it is a physical defect that has been associated with significant impairments in self-esteem, communication, nutrition, and perceptions of appearance. This study aimed to evaluate the survival rate and prosthetic complications of implant-supported overdentures in the edentulous upper jaw ...
Khan, A. A. M, Zahan, N. P
openaire   +1 more source

Survival rate of etanercept for psoriasis in real life: a multicentre observational study

European Journal of Dermatology, 2014
The classic systemic treatments for psoriasis, such as cyclosporine, methotrexate and phototherapy, are limited by their accumulative toxicity [1] and the new generation of monoclonal antibody-based treatments is in trial. The concept of treatment survival is defined as the time for which a drug remains a suitable option for a given patient [2] and is ...
Enrique, Herrera-Acosta, Jorge A, Suárez-Pérez, José, Aguilera, Francisco, Gómez-García, Rafael, Jiménez-Puya, Francisco, Guimerá, Maria V, Mendiola, Enrique, Herrera-Ceballos   +7 more
openaire   +2 more sources