Results 101 to 110 of about 256,970 (318)

Gravitational interactions with information dynamics

open access: yesFrontiers in Astronomy and Space Sciences
IntroductionUnifying gravity with quantum mechanics remains a cornerstone challenge in physics, with information theory providing a transformative perspective through concepts like the holographic principle and entropic gravity.MethodsWe derive an ...
Mahgoub A. Salih
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Workshop on the evolution of the Martian atmosphere [PDF]

open access: yes
Thirty-three papers based on the state of our knowledge prior to the anticipated new results from Mars Observer were presented at the workshop. Because of the nature of the subject, the scope of the papers covered a broad disciplinary range encompassing ...
Jakosky, B. M., Luhmann, J. G.
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The importance of the observer in science

open access: yes, 2005
The concept of {\em complexity} (as a quantity) has been plagued by numerous contradictory and confusing definitions. By explicitly recognising a role for the observer of a system, an observer that attaches meaning to data about the system, these ...
Standish, Russell K.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Cosmological networks

open access: yesNew Journal of Physics, 2014
Networks often represent systems that do not have a long history of study in traditional fields of physics; albeit, there are some notable exceptions, such as energy landscapes and quantum gravity.
Marián Boguñá   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Towards Relational Foundations for Spacetime Quantum Physics

open access: yesUniverse
Rovelli’s relational interpretation of quantum mechanics tells us that the description of a system in the formalism of quantum mechanics is not an absolute but is relative to the observer itself.
Pietro Dall’Olio, José A. Zapata
doaj   +1 more source

Psychological Spacetime

open access: yesSAGE Open, 2016
It has been an accepted scientific fact in physics for almost 100 years that time speeds up and slows down for an observer based on factors—such as motion and gravity—that affect space.
Lucian Gideon Conway   +2 more
doaj   +1 more source

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