Results 221 to 230 of about 5,120,899 (402)

Evaluation of inter-observer variation for computed tomography identification of childhood interstitial lung disease. [PDF]

ERJ Open Res, 2019
Jacob J, Owens CM, Brody AS, Semple T, Watson TA, Calder A, Garcia-Peña P, Toma P, Devaraj A, Walton H, Moreno-Galdó A, Aurora P, Rice A, Vece TJ, Cunningham S, Altmann A, Wells AU, Nicholson AG, Bush A.   +18 more
europepmc   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation [PDF]

, 2018
Fabian Bartel, Marcel van Herk, Hugo Vrenken, F. Vandaele, Stefan Sunaert, Katrien De Jaeger, N. J. Dollekamp, C. Carbaat, Emmy Lamers, Edith Dieleman, Yolande Lievens, Dirk De Ruysscher, S. B. Schagen, M. B. de Ruiter, Jan C. de Munck, J. Belderbos   +15 more
openalex   +1 more source

Computational Approaches and Observer Variation in the 3D Musculoskeletal Modeling of the Heads of Anolis. [PDF]

Integr Org Biol
Lagorio AD, McGechie FR, Fields MG, Fortner J, Mackereth E, Perez C, Wilken AT, Leal M, Ward CV, Middleton KM, Holliday CM.   +10 more
europepmc   +1 more source

Variational Inference for Quantifying Inter-observer Variability in Segmentation of Anatomical Structures

, 2022
Xiaofeng Liu, Fangxu Xing, Thibault Marin, Georges El Fakhri, Jonghye Woo   +4 more
openalex   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Artificial intelligence-generated targets and inter-observer variation in online adaptive radiotherapy of bladder cancer. [PDF]

Phys Imaging Radiat Oncol
Åström LM, Sibolt P, Chamberlin H, Serup-Hansen E, Andersen CE, van Herk M, Mouritsen LS, Aznar MC, Behrens CP.   +8 more
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

567 Psoriasis severity assessment with a computational similarity-clustering programme reduces intra- and inter-observer variation [PDF]

, 2018
Arman Garakani, Ionela Manole, W. Walmink, Andreas Rössler, Janez Žibert   +4 more
openalex   +1 more source

Gleason’s Grading of Prostatic Adenocarcinoma: Inter-Observer Variation Among Seven Pathologists at a Tertiary Care Center in Oman [PDF]

Asian Pac J Cancer Prev, 2016
Qureshi A, Lakhtakia R, AL Bahri M, Al Haddabi I, Saparamadu A, Shalaby A, Shalaby A, Al Riyami M, Rizvi G.   +8 more
europepmc   +1 more source