Results 81 to 90 of about 83,343,124 (294)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Computation of minimal order dynamic covers for predic systems [PDF]
, 2007 - Minimal dimension dynamic covers play an important role in solving the structural synthesis problems of minimum order functional observers or fault detectors, or in computing minimal order inverses or minimal degree solutions of model matching problems.
Varga, Andreas
core
Impulsive functional observers for linear systems
, 2011 The impulsive functional observer design problem for linear systems is addressed. Piecewise differentiable Lyapunov functions are introduced to analyze the stability of the error dynamics.
Dan-Xia Li +5 more
core +1 more source
H ∞ sliding mode observer design for a class of nonlinear discrete time-delay systems: A delay-fractioning approach [PDF]
, 2011 Copyright @ 2012 John Wiley & SonsIn this paper, the H ∞ sliding mode observer (SMO) design problem is investigated for a class of nonlinear discrete time-delay systems.
Zidong Wang +7 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Reconstructing initial data using iterative observers for wave type systems. A numerical analysis [PDF]
, 2011 A new iterative algorithm for solving initial data inverse problems from partial observations has been recently Proposed in Ramdani et al. (Automatica 46(10), 1616–1625, 2010).
Haine, Ghislain, Ramdani, Karim
core
New observer and state estimates to nonlinear systems with real-order derivatives
Franklin OpenThe problem of constructing an observer system to nonlinear systems with real-order derivatives seems a very new issue in advanced control theory.
Bichitra Kumar Lenka +1 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source