Results 31 to 40 of about 1,896,726 (260)

Stepping over obstacles: Attention demands and aging

, 2009
Older adults have been shown to trip on obstacles despite taking precautions to step carefully. It has been demonstrated in dual-task walking that age-related decline in cognitive and attentional mechanisms can compromise postural management. This is yet
Harley, C., Wann, J.P., Wilkie, R.M.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Perspectives in the Scientific Literature on the Barriers and Benefits of the Transition to a Plant-Based Diet: A Bibliometric Analysis

Foods
Plant-based diets are increasingly attracting attention as they play a significant role in human health and environmental sustainability and are believed to be key components of sustainable food systems.
Lelia Voinea, Ana-Maria Badea, Răzvan Dina, Dorin Vicențiu Popescu, Mihaela Bucur, Teodor Mihai Negrea   +5 more
doaj   +1 more source

Obstacles to The Application of Total Quality Management in The Administrative Aspects of The Colleges of Education in The Palestinian Universities

المجلة العربية لضمان جودة التعليم الجامعي, 2016
The present study aimed to identify the obstacles to the application of TQM in the administrative aspects of the colleges of education in Palestinian universities.
Ahmed Ghoneem Abu EL-Khaeir
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Obstacles Face the Jordanian Universities to Promote Learning the Political Concept from the Perspective of Faculty Members

المجلة العربية لضمان جودة التعليم الجامعي, 2015
The study aimed to identify the obstacles facing the Jordanian universities in promoting the concepts of political education from the standpoint of the faculty members, and the relationship of the variables (sex , university, and academic rank ...
Reda Mawadiah, Hussain Hameed Shdefat, Mohammad Saleem Azboon   +2 more
doaj   +1 more source

A Data-driven Model for Interaction-aware Pedestrian Motion Prediction in Object Cluttered Environments

, 2018
This paper reports on a data-driven, interaction-aware motion prediction approach for pedestrians in environments cluttered with static obstacles. When navigating in such workspaces shared with humans, robots need accurate motion predictions of the ...
Cadena, Cesar, Nieto, Juan, Paolo, Giuseppe, Pfeiffer, Mark, Siegwart, Roland, Sommer, Hannes   +5 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Obstacles:

IEEJ Transactions on Industry Applications, 2017
This chapter discusses the obstacles which were put in the way of those who wanted to cross the front line from the Red Army to the Wehrmacht. These obstacles were higher here than at other fronts. In addition to the normal military obstacles to crossing the line, and the widespread moral imperatives against betraying the fatherland, came threats to ...
  +5 more sources

Overcoming the Obstacles to Addressing Racism [PDF]

, 2018
Antiracist scholars Ibram Kendi and Robin DiAngelo urge RWU community to focus on outcomes of policies and to think of racism as a structure, not an ...
Fitzpatrick, Edward
core   +1 more source