Results 31 to 40 of about 108,085 (245)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Road from Medical Injury to Claims Resolution: How No-Fault and Tort Differ [PDF]

, 1997
In the area of medical malpractice, no-fault has been offered as a response to the criticisms leveled against tort litigation for medical injuries.
Entman, Stephen S., Kulas, Elizabeth D., Sloan, Frank A., Stout, Emily M., Whetten-Goldstein, Kathryn   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimal programmed intermittent epidural bolus volume for dural puncture epidural labor analgesia in patients with gestational hypertension: a biased-coin up-and-down sequential allocation trial

Frontiers in Medicine
BackgroundThis study aimed to evaluate the effective programmed intermittent epidural bolus (PIEB) volume and the efficacy of dural puncture epidural (DPE) for labor analgesia in patients with gestational hypertension (GH).MethodsFifty primiparous women ...
Binghui Zhang, Hongyang Zhang, Yuan Wu, Kai Zhao, Yancen Meng   +4 more
doaj   +1 more source

Correlation between vaginal microecology, glycolipid metabolism levels and pregnancy outcome in patients with gestational diabetes mellitus

Zhongguo linchuang yanjiu, 2023
Objective To investigate vaginal microecology, glycolipid metabolism levels in patients with gestational diabetes mellitus (GDM), and their correlation with pregnancy outcome.
WU Qinjuan, LEI Xiaolin, HUANG Xiaochun, CHEN Xunyan   +3 more
doaj   +1 more source

Obstetrical aspects in congenital ichtyosis [PDF]

, 2016
We present a case of congenital ichthyosis because obstetrical literature is scarce and most obstetricians could need a reminder and update. Congenital ichthyosis (CI) comprises a variety of skin disorders characterised by abnormal keratinization of the ...
Dehaene, Isabelle, Page, Ann-Sophie, Page, Geert   +2 more
core  

Antenatal corticosteroids-to-birth interval in preterm birth [PDF]

, 2021
Objectives: The purpose of this study was to compare short-term outcomes in children born between 24 and 34 weeks’ gestation, according to observed antenatal corticosteroids (ACS)-to-birth intervals.
De Coen, Kris, Decruyenaere, Johan, Dehaene, Isabelle, Oostra, Anna, Roelens, Kristien, Smets, Koenraad   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Network meta-analysis: comparative efficacy of diverse aspirin dosages and heparin in mitigating placenta-mediated pregnancy complications

BMC Pregnancy and Childbirth
Objective This study aimed to assess the comparative efficacy of different low-dose aspirin (ASA) dosages, either alone or in combination with heparin, in preventing placenta-mediated pregnancy complications (PMPC) among high-risk pregnant women using a ...
Zhihui Xiong, Shenglin Jiang, Zhouhui Yuan, Lijie Li, Yunmeng Chen   +4 more
doaj   +1 more source

Pain Ratings and Pharmacological Pain Management in Australian Breastfeeding Women After a Caesarean Section Birth

Proceedings
Caesarean section (CS) birth is associated with pain and reduced mobility that impacts a woman’s ability to breastfeed and care for her newborn infant [...]
Jasmine E. Hunt, Philip Vlaskovsky, Ching T. Lai, Sarah G. Abelha, Jacki L. McEachran, Stuart A. Prosser, Donna T. Geddes, Sharon L. Perrella   +7 more
doaj   +1 more source