Results 91 to 100 of about 175,708 (350)

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Assessment of Students’ Satisfaction on Academic Environment, Clinical Skills and Examinations in Obstetrics and Gynecology Course of Under Graduate Curriculum

Asian Journal of Medical Sciences, 2013
Background: During the last decade efforts has been made globally by academic experts in changing curriculum with essential requirements and core competences, so that medical graduates must become a good physician.
Malak Mohammed Musaed Al-Hakeem
doaj   +1 more source

Looking at the Unborn: Historical aspects of obstetric ultrasound [PDF]

, 2000
Edited trascript of a Witness Seminar held at the Wellcome Institute for the History of Medicine,in London, on 10 March 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Christie, DA, Tansey, EM
core  

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

Advanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang, Zhi‐Xue Song, Si‐Ming Bu, Yi‐Mei Liu, Qing Li, Wen‐Xia Zhang, Xu‐Rong Sun, Xin Zhang, Yu‐Xuan Xiao, Di Bo, Xu‐Bin Miao, Chao Liu, Xin‐Hua Zhang, Lei Zheng, Hong‐Ye Zhao, Bao‐Lian Zhang, Wen Jia, Kui Chi, Yu Liu, Yong‐Bo Zhao, Bin Zheng, Dong Ma, Jin‐Kun Wen   +22 more
wiley   +1 more source

Sequential Tumor Microenvironment Reprogramming by Nanoplatform Potentiates Sonodynamic‐Chemodynamic Therapy and Immune Checkpoint Blockade in Breast Cancer

Advanced Science, EarlyView.
A modular nanoplatform capable of sequentially reprogramming tumor microenvironment via cascade actions and responsive therapeutic functions is reported for breast cancer therapy. Via a dual‐targeting mechanism and responsive PD‐L1 antibody release, this nanoplatform enables amplified sonodynamic‐chemodynamic therapy and elicits robust immune response ...
Yang Yu, Zheming Song, Anni Zhu, Jingchao Li, Rujia Fan, Bing Xiao   +5 more
wiley   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

Erratum : « Directive clinique N° 390-Classification et prise en charge de l'hyperplasie de l'endomètre » [Journal of Obstetrics and Gynaecology Canada 41/12 (2019) 1801–1813] [PDF]

, 2020

openalex   +1 more source

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

Advanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen, Yuexuan Xu, Ying Xu, Xiao Liu, Yuting Zhang, Dan Ye, Sai Han, Shili Liu, Youzhong Zhang   +8 more
wiley   +1 more source

‘Standardized patients’ in teaching the communication skill of history-taking to four-year foreign medical undergraduates in the department of obstetrics and gynaecology

BMC Medical Education, 2019
Background Many foreign students have difficulty taking histories from Chinese patients, especially in clinical context of the Department of Obstetrics and Gynaecology.
Jing Zhang, Meng Cheng, Na Guo, Aiyun Xing, Liangzhi Xu   +4 more
doaj   +1 more source

GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy

Advanced Science, EarlyView.
Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang, Yedong Tang, Xueling Zhao, Yu Ni, Hualan Zhou, Enhao Zhang, Gaizhen Li, Han Cai, Yinan Wang, James R. Woodgett, Wenbo Deng, Haibin Wang, Zhongxian Lu, Haili Bao, Shuangbo Kong   +14 more
wiley   +1 more source