Results 91 to 100 of about 317,686 (280)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Functional evaluation of the urinary tract by duplex Doppler ultrasonography in patients with acute renal colic

International Journal of Nephrology and Renovascular Disease, 2011
Raza Sayani1, Muhammad Ali1, Kashif Shazlee2, Rana Shoaib Hamid1, Kamran Hamid21Radiology Department, Aga Khan University Hospital, 2Radiology Department, Ziauddin Hospital, Karachi, PakistanPurpose: To determine the role of duplex Doppler ...
Sayani R, Ali M, Shazlee K, Hamid RS, Hamid K   +4 more
doaj  

Post-operative transmesosigmoid hernia causing small bowel obstruction: a case report

The Pan African Medical Journal, 2015
Internal hernia is an unusual cause of small bowel obstruction and classified several types according to locations.Transmesosigmoid hernia is rare type among others mesosigmoid hernia was rarely reported in the literature. We report the case of a 44-year-
Robleh Hassan Farah, Yassine Fahmi, Driss Khaiz, Khalid Elhattabi, Fatimazahra Bensardi, Rachid Lefriyekh, Saad Berrada, Abdelaziz Fadil, Najib Zerouali Ouariti   +8 more
doaj   +1 more source

Diagnostic accuracy of capnovolumetry for the identification of airway obstruction – results of a diagnostic study in ambulatory care

Respiratory Research, 2019
Background One of the known weaknesses of spirometry is its dependence on patients’ cooperation, which can only partially be alleviated by educational efforts. Therefore, procedures less dependent on cooperation might be of value in clinical practice. We
Christina Kellerer, Neele Jankrift, Rudolf A. Jörres, Klaus Klütsch, Stefan Wagenpfeil, Klaus Linde, Antonius Schneider   +6 more
doaj   +1 more source

Automatic delineation and quantification of pulmonary vascular obstruction index in patients with pulmonary embolism using Perfusion SPECT-CT: a simulation study. [PDF]

EJNMMI Phys, 2021
Bourhis D, Wagner L, Rioult J, Robin P, Le Pennec R, Tromeur C, Salaün PY, Le Roux PY.   +7 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Peak Index: Spirometry Metric for Airflow Obstruction Severity and Heterogeneity

Annals of the American Thoracic Society, 2019
Abstract Rationale Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation. Spirometry loops are not smooth curves and have undulations and peaks that likely reflect heterogeneity of airflow. Objectives
Surya P. Bhatt, Sandeep Bodduluri, Vrishank Raghav, Nirav R. Bhakta, Carla G. Wilson, Young-il Kim, Michael Eberlein, Frank C. Sciurba, MeiLan K. Han, Mark T. Dransfield, Arie Nakhmani   +10 more
openaire   +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The BODE index predicted death in chronic obstructive pulmonary disease [PDF]

ACP Journal Club, 2004
Source Citation Celli BR, Cote CG, Marin JM, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med.
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source