Results 81 to 90 of about 317,686 (280)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Phenotypic differences in airway obstruction as determined by VOTE score

World Journal of Otorhinolaryngology-Head and Neck Surgery
Objective The objective if this study was to investigate phenotypic differences in airway obstruction, as determined by VOTE score, in a cohort of patients with obstructive sleep apnea (OSA) undergoing drug‐induced sleep endoscopy (DISE).
Andrew S. Franklin, Paul M. Putnam, Meghana C. Chanamolu, Chad A. Nieri, M. Boyd Gillespie   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Quantification of the pulmonary vascular obstruction index on ventilation/perfusion lung scintigraphy: Comparison of a segmental visual scoring to the Meyer score. [PDF]

Front Med (Lausanne), 2022
Le Pennec R, Tromeur C, Orione C, Robin P, Le Mao R, Gut-Gobert C, Le Gal G, Salaün PY, Le Roux PY.   +8 more
europepmc   +1 more source

Body mass index and fat free mass index in obstructive lung disease in Korea

The International Journal of Tuberculosis and Lung Disease, 2014
To investigate the relationship between body mass index (BMI), fat free mass index (FFMI) and obstructive lung disease in Korea.Based on a large population-based, nationwide survey conducted in Korea, 822 subjects with airway obstruction and the same number of healthy control subjects were selected.
S B, Kim, Y A, Kang, J Y, Jung, M S, Park, Y S, Kim, S K, Kim, J, Chang, E Y, Kim   +7 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Doppler sonography in acute renal obstruction

Indian Journal of Radiology and Imaging, 2007
Aims and Objectives: This prospective analysis was carried out to study the utility of Doppler waveform alterations in the diagnosis of unilateral acute renal obstruction and to study the factors affecting Doppler indices.
Sonali S Saboo, Sachin S Soni, Suresh H Saboo, Naga Ramesh Chinapuvvula, Sashidhar Kaza   +4 more
doaj   +1 more source

Positive scalar curvature on manifolds with fibered singularities

, 2019
A (compact) manifold with fibered $P$-singularities is a (possibly) singular pseudomanifold $M_\Sigma$ with two strata: an open nonsingular stratum $\mathring M$ (a smooth open manifold) and a closed stratum $\beta M$ (a closed manifold of positive ...
Botvinnik, Boris, Rosenberg, Jonathan
core  

Modified bladder outlet obstruction index for powerful efficacy prediction of transurethral resection of prostate with benign prostatic hyperplasia. [PDF]

BMC Urol, 2021
Liu H, Tian Y, Luo G, Su Z, Ban Y, Wang Z, Sun Z.   +6 more
europepmc   +1 more source