Results 61 to 70 of about 522,787 (267)

Obstructive Nephropathy.

Internal Medicine, 2000
Obstructive nephropathy is a relatively common entity that is treatable and often reversible. It occurs at all ages from infancy to elderly subjects. Obstructive uropathy is classified according to the degree, duration and site of the obstruction. It is the result of functional or anatomic lesions located in the urinary tract. The causes of obstructive
openaire   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
Suna Lin, Linjie Li, JiJun Chen, Zhaokun Tao, Lifeng Zhang, Junqing Mao, Jinhu Wang   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Low lung function in Bipolar Disorder and Schizophrenia: a hidden risk

Frontiers in Physiology
Introduction: People with serious mental illness (SMI), such as schizophrenia and bipolar disorder, have a higher risk of premature morbidity and mortality.
Cristina Ruiz-Rull, Cristina Ruiz-Rull, María José Jaén-Moreno, María José Jaén-Moreno, Gloria Isabel del Pozo, Gloria Isabel del Pozo, Cristina Gómez, Cristina Gómez, Francisco Javier Montiel, Francisco Javier Montiel, Montserrat Alcántara, Montserrat Alcántara, Laura Carrión, Laura Carrión, Geli Marie Chauca, Geli Marie Chauca, Nuria Feu, Ipek Guler, Fernando Rico-Villademoros, Cristina Camacho-Rodríguez, Luis Gutierrez-Rojas, Luis Gutierrez-Rojas, David Mannino, Fernando Sarramea, Fernando Sarramea, Fernando Sarramea, Fernando Sarramea   +26 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Pathophysiology of obstructive sleep apnoea syndrome: a review

Sultan Qaboos University Medical Journal, 2000
Sleep apnoea syndrome is a common disorder and a major health hazard that affects many body systems. It is particularly associated with increased cardiovascular and cerebrovascular morbidity and mortality. Among its other manifestations include increased
Al Riyami B, Al Rawas O, Hassan MO
doaj  

Wind Instrument Training and Sound-Based Interventions for Sleep Quality and Obstructive Sleep Apnoea: A Narrative Synthesis

Noise and Health
Background: Tolerability issues with continuous positive airway pressure (CPAP) therapy for obstructive sleep apnoea (OSA) have spurred interest in nonpharmacological alternatives like sound-based interventions (wind instrument training, singing and ...
Yi Ding, KaiLi Jiang
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Prognostic Factors Related to Sleep Quality in Patients With Obstructive Sleep Apnea After Positive Airway Pressure Therapy [PDF]

Journal of Rhinology
Background and Objectives This study aimed to evaluate the factors that influence deep sleep restoration in patients with obstructive sleep apnea (OSA) following positive airway pressure (PAP) therapy.
Dong Heun Park, Hangseok Choi, Kukjin Nam, Seung Hoon Lee, Min Young Seo   +4 more
doaj   +1 more source