Results 121 to 130 of about 306,427 (235)

[Sudden death in hypertrophic obstructive and non-obstructive cardiomyopathy: can it be prevented?]

open access: yes, 1997
Sudden cardiac death constitutes the most devastating aspect of obstructive and non-obstructive hypertrophic cardiomyopathy. Loss of consciousness and family history of sudden cardiac death should alert the physician to the risk of sudden death.
Schlaepfer, J.   +3 more
core  

Free left ventricular wall rupter in a newborn. [PDF]

open access: yes, 2015
Free left ventricular wall rupture is very rare but mostly fatal complication of acute myocardial infarction in the elderly. Without the presence of congenital heart disease, preceding cardiac surgery or an isolated ventricular diverticulum ...
Wagner, Bendicht Peter   +9 more
core   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He   +4 more
wiley   +1 more source

Understanding the Mortality Trends in Patients With Ventricular Arrhythmias and Cardiomyopathy: A 25‐Year Retrospective Analysis From 1999–2024

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 6, November 2026.
Central illustration depicting trends in demographics and differences in Ventricular Arrhythmias with Cardiomyopathy‐related Mortality among adults in the United States from 1999 to 2024. ABSTRACT Background Ventricular Arrhythmias (VA) associated with Cardiomyopathy (CM) continues to be the major cause of death.
Nosheen Pervaiz   +8 more
wiley   +1 more source

Mitral Transcatheter Edge-to-Edge Repair in Non-Surgical Candidates with Hypertrophic Obstructive Cardiomyopathy: Clip It, or Ablate It?

open access: yesJournal of Cardiovascular Development and Disease
Hypertrophic cardiomyopathy (HCM), with or without obstructive phenomena, remains underdiagnosed and undertreated. This condition often involves pathological changes in the mitral valve leaflets and apparatus, which can lead to relevant mitral ...
Emmanouil Chourdakis   +3 more
doaj   +1 more source

Genetic Spectrum of Non‐PTPN11 Variants in Noonan Syndrome and Related RASopathies: Findings From a Russian Cohort

open access: yesClinical Genetics, Volume 110, Issue 5, Page 527-537, November 2026.
Noonan syndrome and related conditions are caused by variants in multiple genes. We analyzed 456 Russian patients using a 23‐gene panel and found disease‐causing variants in non‐PTPN11 genes in 85 cases. NF1, SOS1, BRAF, and SHOC2 explained half of these diagnoses.
Anna Orlova   +5 more
wiley   +1 more source

Effects of Moderate Spine Exercise or Diet on Hemodynamics in Patients with Hypertrophic Obstructive Cardiomyopathy and Aortic Stenosis [PDF]

open access: yes
Left ventricular outflow tract stenosis is present in patients with hypertrophic cardiomyopathy; however, this is a dynamic change, and the pressure gradient changes easily.
Mizuguchi, Satoshi   +4 more
core   +2 more sources

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita

open access: yesClinical Genetics, Volume 110, Issue 5, Page 584-589, November 2026.
We report on two individuals with arthrogryposis multiplex congenita who were heterozygous for ACTC1 missense variants (NM_005159.5; c.325G>A, p.Glu109Lys and c.650A>C, p.Lys217Thr) and provide a characterization of these variants through in vitro studies.
Lauren Kerr   +5 more
wiley   +1 more source

Attenuated Cardiac–Ocular Phenotype of Sanfilippo Syndrome (MPS IIIA) Presenting With Hypertrophic Cardiomyopathy and Cone-Rod Dystrophy

open access: yesAnnals of Internal Medicine: Clinical Cases
We describe a 39-year-old woman with cone-rod dystrophy and hypertrophic obstructive cardiomyopathy complicated by an apical aneurysm, ventricular tachycardia, and ischemic stroke, ultimately requiring heart transplantation.
Marc Vanderheyden   +2 more
doaj   +1 more source

Myosin Inhibitors for Hypertrophic Obstructive Cardiomyopathy (HOCM): Is HOCM passing another Crossroad?

open access: yes
Lawrenz T, Lawin D, Stellbrink C. Myosin Inhibitors for Hypertrophic Obstructive Cardiomyopathy (HOCM): Is HOCM passing another Crossroad?
Lawrenz, Thorsten   +2 more
core   +1 more source

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