Results 121 to 130 of about 4,753,165 (342)

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Faecal occult blood test: Current practice in a rural Queensland community [PDF]

, 2002
The findings of a recent telephone survey of 604 residents (50-74 years of age) in a rural community in Queensland are presented. The survey focused on the participants' knowledge concerning the faecal occult blood test (FOBT) and their previous testing ...
Warren R. Stanton, Tong, Shilu, Stanton, Warren R., Del Mar, Christopher, Monika Janda, Alexandra Clavarino, Leggett, Barbara, Clavarino, Alexandra, Christopher Del Mar, Short, Leonie, Hughes, Karen, Leggette, Barbara, Joanne Aitken, Aitken, Joanne, Leonie Short, Stanton, Warren, Beth Newman, Janda, Monika, Karen Hughes, Delmar, Christopher, Newman, Beth, Shilu Tong, Barbara Leggett   +22 more
core   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

A preliminary assessment of a stool-based microRNA profile for early colorectal cancer screening

Scientific Reports
Colorectal cancer screening methods are well established worldwide as a fundamental pilar in CRC management, namely through non-invasive faecal occult blood testing.
Daniela A. R. Santos, Mariana Eiras, Miguel Gonzalez-Santos, Marlene Santos, Carina Pereira, Lúcio Lara Santos, Mário Dinis-Ribeiro, Luís Lima   +7 more
doaj   +1 more source

Assessment of the adherence and willingness to participate in colorectal cancer screening programs among people living in prison.

PLoS ONE
This study aimed to assess the adherence and willingness to participate in colorectal cancer screening programs in people living in prison (PLP). This survey was conducted from October 2023 and July 2024.
Giovanna Paduano, Gabriella Di Giuseppe, Mario Postiglione, Giuseppe Nese, Sabrina Morra, Maria Pavia   +5 more
doaj   +1 more source

HBV vaccination of HCV-infected patients with occult HBV infection and anti-HBc-positive blood donors

Brazilian Journal of Medical and Biological Research, 2006
Anti-HBc positivity is a frequent cause of donation rejection at blood banks. Hepatitis B virus (HBV) infection may also occur in HBsAg-negative patients, a situation denoted occult infection. Similarly, very low levels of HBV-DNA have also been found in
J.S.F. Pereira, N.S.L. Gonçales, C. Silva, M.S.K. Lazarini, M.H.P. Pavan, V.C. Fais, F.L. Gonçales Júnior   +6 more
doaj   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Forest plot of Occult HBV infection among Chinese volunteer blood donors. [PDF]

, 2013
Forest plot of Occult HBV infection among Chinese volunteer blood donors.
Yang Zheng (185762), Yan Deng (159032), Guang-ying Liu (483971), Guo-yuan Sui (483970), Yan-yan Gao (483972), Lie Wang (117337), Guang-cong Liu (483969)   +6 more
core   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Clinicopathologic Significance of Immunohistochemical Fecal Occult Blood Test in Subjects Receiving Bidirectional Endoscopy [PDF]

, 2008
Background/Aims: Fecal occult blood test has been,utilized to screen for lower gastrointestinal pathologies. such as colorectal cancer and polyps that bleed. Recent studies have revealed a relatively high frequency of upper gastrointestinal abnormalities
王德宏;林肇堂, WANG, TEH-HONG;LIN, JAW-TOWN   +1 more
core