Results 41 to 50 of about 2,220,228 (297)

Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening

BMC Medicine, 2023
Background Colorectal cancer (CRC) screening reduces all-cause and CRC-related mortality. New research demonstrates that the faecal haemoglobin concentration (f-Hb) may indicate the presence of other serious diseases not related to CRC.
Lasse Kaalby, Ulrik Deding, Issam Al-Najami, Gabriele Berg-Beckhoff, Thomas Bjørsum-Meyer, Tinne Laurberg, Aasma Shaukat, Robert J. C. Steele, Anastasios Koulaouzidis, Morten Rasmussen, Morten Kobaek-Larsen, Gunnar Baatrup   +11 more
doaj   +1 more source

The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort. [PDF]

, 2015
Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection ...
Labbett, W, Patel, M, O'Riordan, A, Davenport, A, Sowole, L, Haque, T, Cross, J   +6 more
core  

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Fabio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

A rare cause of obscure gastrointestinal bleeding: Chronic enteropathy associated with SLCO2A1 mutation in a case from India

International Journal of Gastrointestinal Intervention
A 13-year-old boy presented with an 8-year history of repeated episodes of anemia. Laboratory investigations confirmed iron deficiency anemia due to occult blood loss from the gastrointestinal tract.
Shivani Chopra, Vikramaditya Rawat, Meghraj Ingle, Saiprasad Lad, Mit Shah, Deepak Sasikumar, Vinay Borkar, Yatin Lunagariya, Somraj Patil   +8 more
doaj   +1 more source

Comparison of Multiplex Real-Time Polymerase Chain Reaction Assays for Detection of Respiratory Viruses in Nasopharyngeal Specimens

Annals of Clinical Microbiology, 2019
Background: Respiratory tract infections are major public health threats, and the identification of their causative microbes helps clinicians to initiate timely and appropriate antimicrobial therapy and prevent the secondary spread of infection. The main
, Min Kyung Kim, Daewon Kim, Jung-Hyun Byun, Dongeun Yong   +4 more
doaj   +1 more source

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease [PDF]

, 2012
A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid, Wolters, Dirk, Heiß, Christian, Rodriguez Mateos, Ana, Krenz, Thomas, Kuhnle, G. G. C., Cortese-Krott, Miriam M, Rodriguez-Mateos, Ana, Kelm, Malte, Cortese-Knott, Miriam M., Feelisch, Martin, Rodriguez-Mateos, Z, Kroncke, K.-D., Kröncke, Klaus-Dietrich, Sansone, R., Kuhnle, Gunter G. C., Kelm, M., Heiss, C., Krisp, C., Sansone, Roberto, Horn, P., Feelisch, M., Horn, Patrick, Krisp, Christoph, Krenz, T., Hogg, N., Kuhnle, Gunter, Kuhnle, Gunter G.C., Thasian-Sivarajah, S., Thasian-Sivarajah, Sivatharsini, Wolters, D., Cortese-Krott, Miriam M., Hogg, Neil, Cortese-Krott, M. M.   +33 more
core   +1 more source

Occult hepatitis C virus infection in volunteer blood donors in Shaanxi province

, 2022
Objective To investigate the prevalence of occult hepatitis C virus infection (OCI) in Shaanxi blood donors and characterize the occult hepatitis C virus in this cohort.
Xiaohua ZHAO, Hua XU, Chen HE, Yan GUO, Guoquan ZHANG, Jin LI, Yong DUAN, Wen WANG   +7 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

The analysis of immunochemical fecal occult blood test results in colorectal cancer screening in Shanghai

Zhongguo aizheng zazhi, 2018
Background and purpose: Shanghai provides free colorectal cancer screening services to eligible residents. This study aimed to analyze immunochemical fecal occult blood test results in colorectal cancer screening to assess the effectiveness of twice ...
龚杨明, 鲍萍萍
doaj