Results 71 to 80 of about 18,100 (221)

Indeterminate Phase/Grey Zone of Chronic Hepatitis B: Clinical Features, Outcomes and Molecular Insights

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a global public health challenge, with a high risk of complications such as cirrhosis, hepatocellular carcinoma (HCC) and death. As outlined in current international society guidelines, antiviral therapies are aimed at preventing progression of liver disease to life‐threatening complications ...
Maria Stella Franzè, Teresa Pollicino, Jean‐Michel Pawlotsky, Vincent Leroy, Giovanni Raimondo, Giuliana Amaddeo   +5 more
wiley   +1 more source

Occult hepatitis B in patients on hemodialysis: a review

Annals of Hepatology, 2013
The hepatitis B virus (HBV) is one of the most frequently transmitted agents in dialysis units. Occult hepatitis B is characterized by HBV infection without detectable surface antigen (HBsAg) in the patient’s serum, a positive or negative HBV DNA marker ...
Andrea M.M. Fontenele, Pharm, MSc., Natalino Salgado Filho, Adalgisa S.P. Ferreira   +2 more
doaj   +1 more source

Molecular Mechanisms Underlying Occult Hepatitis B Virus Infection [PDF]

Clinical Microbiology Reviews, 2012
SUMMARYChronic hepatitis B virus (HBV) infection is a complex clinical entity frequently associated with cirrhosis and hepatocellular carcinoma (HCC). The persistence of HBV genomes in the absence of detectable surface antigenemia is termed occult HBV infection.
Jasmine, Samal, Manish, Kandpal, Perumal, Vivekanandan   +2 more
openaire   +2 more sources

A Quantitative Systems Pharmacology (QSP) Model of Acute Hepatitis B Virus Infection: Mechanistic Insights and Foundations for Future Extensions

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a significant global health challenge. While the dynamic interplay between viral replication and host immune responses determines infection outcomes, the mechanisms driving the resolution of acute infection versus the emergence of chronicity remain incompletely understood.
Clémence Boivin‐Champeaux, Stephan Schmidt, Scott Balsitis, Francine Johansson Azeredo, Justin S. Feigelman   +4 more
wiley   +1 more source

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

Microbiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu, Takehiro Kanda, Ryo Komorizono, Madoka Sakai, Alexander Leacy, Leonardo Susta, Akiko Makino, Keizo Tomonaga   +7 more
wiley   +1 more source

Update on occult hepatitis B virus infection

World Journal of Gastroenterology, 2016
The event of mutations in the surface antigen gene of hepatitis B virus (HBV) results in undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core (anti-HBc) antibody status in serum and this phenomenon is named occult hepatitis B infection (OBI).
openaire   +2 more sources

Exacerbation of Anti‐Cytomegalovirus Immunity and Mobilization of γ9δ1 T Cells During the Acute Phase of Hepatitis E Virus Infection

Microbiology and Immunology, Volume 70, Issue 2, Page 113-124, February 2026.
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Marion Retailleau, Fanny Martini, Florence Abravanel, Nassim Kamar, Jacques Izopet, Eric Champagne   +5 more
wiley   +1 more source

KIR and a specific HLA-C gene are associated with susceptibility and resistance to hepatitis B virus infection in a Brazilian population [PDF]

, 2014
Colsan Associacao Beneficente Coleta Sangue, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Gynecol, São Paulo, BrazilFed Univ Rio de Janeiro UERJ, Inst Biol, Mol Virol Lab, Rio de Janeiro, RJ, BrazilFed Univ Rio de Janeiro UERJ, Histocompatibil ...
Araujo, Patricia, Barreto, Jose Augusto, Castelo Girao, Manoel Joao, Diaz, Ricardo Sobhie, Ferreira, Orlando, Goncalves, Giovana, Latini, Flavia, Porto, Luis Cristovao   +7 more
core   +1 more source

S3 Guideline for the Treatment of Psoriasis vulgaris, adapted from EuroGuiDerm – part 2: Specific clinical and comorbid situations

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 2, Page 270-282, February 2026.
Summary The present Part 2 of the updated German S3 guideline on the treatment of psoriasis vulgaris provides recommendations for therapy selection in special clinical situations and in the presence of comorbidities. A major focus of this update is the chapter on screening for tuberculosis as well as therapy selection and management in latent ...
Alexander Nast, Andreas Altenburg, Matthias Augustin, Frank Bachmann, Wolf‐Henning Boehncke, Markus Cornberg, Hilte Geerdes‐Fenge, Brit Häcker, Peter Härle, Joachim Klaus, Michaela Köhm, Arno Köllner, Ulrich Mrowietz, Hans‐Michael Ockenfels, Antonia Pennitz, Sandra Philipp, Thomas Richter, Thomas Rosenbach, Tom Schaberg, Martin Schlaeger, Gerhard Schmid‐Ott, Michael Sebastian, Karisa Thölken, Ralph von Kiedrowski, Uwe Willuhn, Christoph Zeyen   +25 more
wiley   +1 more source

Hepatitis B Virus (HBV) Reactivation Following Pharmacological Eradication of Hepatitis C Virus (HCV)

Viruses, 2019
The US Food and Drug Administration issued a black box warning related to the risk of reactivation of overt/occult hepatitis B virus (HBV) infection during direct acting-antivirals (DAA) treatment. This review evaluated the prevalence of HBV reactivation
Mariantonietta Pisaturo, Margherita Macera, Loredana Alessio, Federica Calò, Nicola Coppola   +4 more
doaj   +1 more source