Results 91 to 100 of about 290,807 (297)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Implementing housing policies for a sufficient lifestyle

open access: yesBuildings & Cities
The German buildings sector is currently facing a double challenge: meeting emission reduction targets and providing affordable housing in rapidly growing cities.
Mahsa Bagheri   +4 more
doaj   +1 more source

Effects of human disturbance on a burrow nesting seabird

open access: yesRevista Mexicana de Biodiversidad, 2011
During 2004, we followed 72 natural burrows to determine the effects of disturbance on breeding success of Cassin’s auklets (Ptychoramphus aleuticus). We used distance from a human settlement or path in the analysis of disturbance.
Yuri V. Albores-Barajas   +1 more
doaj   +1 more source

Eco-Labeling, Rents, Sales Prices and Occupancy Rates: Do LEED and Energy Star Labeled Offices Obtain Multiple Premiums? [PDF]

open access: yes
Drawing upon an updated and expanded dataset of Energy Star and LEED labeled commercial offices, this paper investigates the effect of eco-labeling on rental rates, sale prices and occupancy rates.
Pat McAllister   +2 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mallard Use of Hen HousesTM in Eastern Ontario

open access: yesAvian Conservation and Ecology, 2006
Nesting structures for ground-nesting waterfowl may be an effective technique for increasing nesting success in regions in which nest success is below the 15% threshold needed to maintain a stable population.
J. Ryan Zimmerling   +3 more
doaj   +1 more source

Occupational Consciousness [PDF]

open access: yesJournal of Occupational Science, 2015
Occupational consciousness refers to ongoing awareness of the dynamics of hegemony and recognition that dominant practices are sustained through what people do every day, with implications for personal and collective health. The emergence of the construct in post-apartheid South Africa signifies the country's ongoing struggle with negotiating long ...
openaire   +2 more sources

Congestive Traffic Failure: The Case for High-Occupancy and Express Toll Lanes in Canadian Cities [PDF]

open access: yes
Congestion on Canadian highways is having a significant negative economic impact on major Canadian cities. Rather than face the political challenge of introducing road tolls to discourage traffic, governments have chosen to build carpool lanes on urban ...
Benjamin Dachis
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Embedding Simplified Post Occupancy Evaluation Within The Design Process

open access: yes, 2011
The project involved the team looking at post occupancy evaluation (POE) analysis from a number of perspectives. The team studied information relating to existing POE methods, current benchmarks to determine industry best practice and compare appropriate
Nugent, Karen   +2 more
core   +2 more sources

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