Results 81 to 90 of about 290,807 (297)

Occupational asthma.

open access: yesEnvironmental Health Perspectives, 1986
Many toxic compounds found in air emissions may induce bronchoconstriction. In the workplace, workers are exposed to these compounds, often in much higher concentrations. Some of these compounds act as sensitizers. Of these, some compounds induce asthma by producing specific IgE antibodies to the compound or its protein conjugate, while others induce ...
openaire   +4 more sources

A study of energy-related occupancy activities in a sample of monitored domestic buildings in the UK [PDF]

open access: yes, 2014
Domestic energy use is determined by multiple non-technological factors, such as the occupants’ lifestyle and activities, which can even offset the effect from energy-efficiency technologies.
Cui, J(M)
core  

An abundance-occupancy time-lag during the decline of an arctiid tiger moth

open access: yes, 2001
The positive interspecific abundance-occupancy relationship is one of the most general patterns in ecology. Positive intraspecific relationships should also exist within species over time, and so a species should occupy more sites in years when it is ...
Ian P. Woiwod   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Occupancy data: unravelling the mystery

open access: yes, 2011
The main purpose of this study was to clarify the method used to calculate bed occupancy ...
Veach, Kate   +6 more
core   +1 more source

Correlation Analysis of Building Performance and Occupant’s Satisfaction via Post Occupancy Evaluation for Malaysia’s Public Buildings [PDF]

open access: yes
The purpose of a building is to provide shelter for activities that carried out by the building users. The question is, does the facilities in the building perform well and appropriate to its use?
Adnan, Hamimah   +3 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Trends and indicators for quantifying moth abundance and occupancy in Scotland [PDF]

open access: yes, 2019
Moths form an important part of Scotland’s biodiversity and an up-to-date assessment of their status is needed given their value as a diverse and species-rich taxon, with various ecosystem roles, and the known decline of moths within Britain. We use long-
Morgan, Byron J. T.   +13 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Occupational asthma

open access: yesThe Lancet, 1997
Occupational asthma is a common disorder that may be caused by several hundred agents and has a variety of pathogenetic mechanisms. Level of exposure is an important risk factor, and reduction of exposure is the only certain method of prevention. Atopy and smoking are further risk factors for IgE-mediated asthma but have not been found to increase risk
Venables, K, Chan-Yeung, M
openaire   +2 more sources

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