Results 81 to 90 of about 543,570 (317)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Misconception: The Experience of Pregnancy for Women with Intellectual Disabilities
Scandinavian Journal of Disability Research, 2007 The experience of pregnancy and motherhood, from a woman's point of view, has only been considered worthy of research in recent decades. In this time, a small number of studies have examined the experiences of mothers with intellectual disabilities.
Rachel Mayes +2 more
doaj +1 more source
Environmental Health Perspectives, 1986 Many toxic compounds found in air emissions may induce bronchoconstriction. In the workplace, workers are exposed to these compounds, often in much higher concentrations. Some of these compounds act as sensitizers. Of these, some compounds induce asthma by producing specific IgE antibodies to the compound or its protein conjugate, while others induce ...
openaire +4 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
BMC Musculoskeletal Disorders, 2017 Background Musculoskeletal disorders are a major health problem resulting in negative effects on wellbeing and substantial costs to society. Work participation is associated with positive benefits for both mental and physical health.
Nathan Hutting +6 more
doaj +1 more source
Occupational Consciousness [PDF]
Journal of Occupational Science, 2015 Occupational consciousness refers to ongoing awareness of the dynamics of hegemony and recognition that dominant practices are sustained through what people do every day, with implications for personal and collective health. The emergence of the construct in post-apartheid South Africa signifies the country's ongoing struggle with negotiating long ...
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Merops apiaster burrow (re)-occupation
, 2015 10 years of individually followed burrows and their (re)-occupation patterns in a German population of the European bee-eater Merops ...
Hans-Valentin Bastian (3257178) +7 more
core +1 more source
Scandinavian Journal of Occupational TherapyBackground People with chronic conditions often experience decreased ability to perform activities of daily living (ADL). ABLE is a structured, client-centred, occupational therapy programme developed to address ADL ability using adaptational strategies.
Vita Hagelskjær +4 more
doaj +1 more source
Frontiers in Environmental HealthBackgroundIn social housing buildings, poor indoor air quality (IAQ) has been shown to be more prevalent, and residents living in social housing areas are often more vulnerable and susceptible to adverse health effects from IAQ.AimTo examine the state ...
Charlotte Gabel +3 more
doaj +1 more source