Results 81 to 90 of about 683,288 (260)
Perspectives on occupation-based social inclusion: Collective occupation in the local, social world [PDF]
, 2018 Keynote lecture presented at the 21st Occupational Science Seminar: "Go back to the origin that links up Occupational Science with clinical practices - questioning 'occupational being' again".
Kantartzis, Sarah
core +2 more sources
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
مجله پژوهش در علوم توانبخشی, 2016 Introduction: Stroke is the acute neurological damage caused by perturbation of blood flow or lack of blood supply to part of the brain tissue and nervous system resulted from cerebral artery occlusion by a blood clot or a ruptured artery.
Saede Shahriarpour +2 more
doaj +1 more source
Occupation-centred paediatric practice Sylvia Rodger's contribution
, 2017 Occupation-centred paediatric practice Sylvia Rodger's ...
Karen Stagnitti (13096053)
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Pilot and Feasibility StudiesBackground People with hand osteoarthritis (HOA) experience difficulties performing activities of daily living (ADL). Referral for occupational therapy is rare despite support for non-pharmacological interventions by international treatment ...
Ulla Andersen +6 more
doaj +1 more source
The Strength of Occupation Indicators as a Proxy for Skill [PDF]
Labor economists have long used occupation indicators as a proxy for unobserved skills that a worker possesses. In this paper, we consider whether inter-occupational wage differentials that are unexplained by measured human capital are indeed due to ...
Levenson, Alec, Zoghi, Cindy
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Revenge and Retribution in the Luxembourgish Occupation Zone in Germany (1945-46)
, 2022 In the winter of 1945, the soldiers of Luxembourg’s occupation army found themselves shifting from vanquished to victors, from occupied to occupiers.
Streicher, Felix; id_orcid
core