Results 91 to 100 of about 230,301 (312)

Conference "Sociale Evaluation of Occupations. Can we Find Universal Values?

open access: yes, 2008
A research project dealing with social evaluation of occupations and professions. From Italian data, light changes in ranking occupations are evident, and gender and territoriality are influencing variables on people ...
GIANNINI, MARIA
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Leisure-time Physical Activity of Polish White-collar Workers: A Cross-sectional Study

open access: yesHong Kong Journal of Occupational Therapy, 2017
Objective/background: The aim of this study was to assess the leisure-time physical activity of Polish white-collar workers in relation to various health recommendations.
Agnieszka Nawrocka   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

A changing occupation: the artisanal fishing told by those who practice (Pelotas, RS)

open access: yesRevista Mundos do Trabalho, 2019
In our society, because of fast technological changes, more and more manual occupations are becoming obsolete, changing or about to disappear. This article intends to discuss these labor transformations, based on the narratives of the professional ...
Lorena Almeida Gill
doaj   +1 more source

Future gender relations in global restructuring processes case study evidence from knowledge-intensive, manufacturing and service occupations [PDF]

open access: yes
Global restructuring processes have not only strong implications for European working and living realities, but also have specific outcomes with regard to gender relations.
Linda Nierling
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Task-Biased Changes of Employment and Remuneration: The Case of Occupations [PDF]

open access: yes
Different empirical studies suggest that the structure of employment in the U.S. and Great Britain tends to polarise into "good" and "bad" jobs. We provide updated evidence that polarisation also occurred in Germany since the mid-1980s until 2008.
Rycx, Francois, Kampelmann, Stephan
core   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A construção de si pela atividade de trabalho: a socialização profissional The construction of self through work activity: the professional socialization

open access: yesCadernos de Pesquisa, 2012
A sociologia funcionalista das profissões distingue dois tipos muito diferentes de atividades de trabalho: as profissões e as ocupações (ambas no sentido que os ingleses lhes dão).
Claude Dubar
doaj   +1 more source

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