Results 101 to 110 of about 730,889 (360)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

A Review on the Social History of Islamic Spain in the Historical and Geographical Sources from the Fourth to the Seventh Century After Hijrah [PDF]

open access: yesتاریخ اسلام, 2012
Andalusia land, separated from the political body of caliphate a little after Islamic conquests, has been the center of attention of historians, geographers, learned people and the other Muslim writers due to its particular climate, historical and ...
Maryam Saeediyan Jazi
doaj  

Some factors influencing occupational engagement for people with schizophrenia living in the community [PDF]

open access: yes, 2002
With the emergence of occupational science, there has been renewed interest in the health benefits of occupational engagement and a call for more research into the occupational nature of humans.
Chugg, A, Craik, C
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Ocupação e hipertensão

open access: yesRevista de Saúde Pública
Com base em revisão bibliográfica discute-se a literatura produzida nas décadas de 70 e 80, no campo da epidemiologia da hipertensão arterial sistêmica entre trabalhadores.
Ricardo Cordeiro   +3 more
doaj  

How General is Specific Human Capital? Using Mobility Patterns to Study Skill Transferability in the Labor Market [PDF]

open access: yes
Previous studies assume that labor market skills are either fully general or specific to a firm. This paper uses patterns in mobility and wages to the transferability of specific skills across occupations.
Christina Gathmann, Uta Schoenberg
core  

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

We Can Work It Out - The Globalisation of ICT-enabled Services [PDF]

open access: yes
This paper examines the relationship between the share of employment potentially affected by offshoring and economic and structural factors, including trade in business services and foreign direct investment (FDI), using simple descriptive regressions ...
Desiree van Welsum, Xavier Reif
core  

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