Results 41 to 50 of about 103,625 (269)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Early Portuguese Data for Wage Developments in India: Kannur (Cananor), 1516-1517

open access: yesLer História, 2019
This essay discusses new evidence for wage developments in Western India from c. 1300 to 1600. By introducing wage and price data for Kannur (Cananor in Portuguese and British sources) for the years 1516-1517 we contribute to a larger discussion about ...
Paulo Teodoro de Matos, Jan Lucassen
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Occupational stress, occupational structure and occupational morbidity

open access: yesInternational Congress Series, 2002
Abstract Occupational stress poses a substantial problem in many countries. Its rates of occurrence and its origins are therefore the subject of substantial research. Competitiveness is an increasingly prominent characteristic of many occupational environments and is considered by some to be essential for occupational advancement and achievement ...
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Cuerpos de mujer en el mundo laboral bilbaíno bajomedieval y moderno (s. XIV –XVI).

open access: yesNuevo mundo - Mundos Nuevos, 2008
Women’s labor was highly regulated in the ordinances and municipal records, and becomes a useful source to appreciate the level of feminine participation in the urban world of Bilbao in the late Middle Ages and in Early Modern period.
Ana María Rivera Medina
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ranking Research Priorities in Health, Safety and Environment (HSE)

open access: yesSalāmat-i kār-i Īrān, 2020
Background  and aims: The diversity of health, safety and environmental issues (HSE) and limitations of the resources hinders response to all the research needs in the field of HSE. HSE promotion and policy making require research based on the real needs
Ali Asghar Farshad   +5 more
doaj  

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

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