Results 61 to 70 of about 730,889 (360)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Highly-educated immigrants and native occupational choice [PDF]
, 2008 Economic debate about the consequences of immigration in the US has largely focused on how influxes of foreign-born labor with little educational attainment have affected similarly-educated native-born workers.
Peri, G., Sparber, C.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ranking Research Priorities in Health, Safety and Environment (HSE)
Salāmat-i kār-i Īrān, 2020 Background and aims: The diversity of health, safety and environmental issues (HSE) and limitations of the resources hinders response to all the research needs in the field of HSE. HSE promotion and policy making require research based on the real needs
Ali Asghar Farshad +5 more
doaj
Journal of Rehabilitation, 2020 Objective: Caring for individuals with multiple sclerosis (MS) can affect their caregivers’ occupational performance in various areas such as work, rest/sleep, and social participation. Part of the rehabilitation process is educating caregivers.
Mohammad Taghi Mohseni Takalu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
eJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2015 This paper argues that the work of teachers can’t be understood solely from the intentionality. It shows how the intentions of the actors are overwhelmed in front of teaching situations.
Frédéric Saujat, Guillaume Serres
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Asian Nursing Research, 2012 Purpose: The purposes of this study are to examine differences in job satisfaction among professional groups including nurses, allied hospital professionals, social workers, and elementary school teachers, and to identify specific characteristics of job ...
Mihyun Park, PhD, RN +2 more
doaj +1 more source
Evaluation of a Rural Telehealth Occupation-Based Coaching Intervention for Type 1 Diabetes Health Management [PDF]
, 2022 Vanessa Jewell +5 more
openalex +1 more source