Results 51 to 60 of about 230,301 (312)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Early Portuguese Data for Wage Developments in India: Kannur (Cananor), 1516-1517
Ler História, 2019 This essay discusses new evidence for wage developments in Western India from c. 1300 to 1600. By introducing wage and price data for Kannur (Cananor in Portuguese and British sources) for the years 1516-1517 we contribute to a larger discussion about ...
Paulo Teodoro de Matos, Jan Lucassen
doaj +1 more source
Engagement of Older Adults in out-of-Home Occupations: Transitioning from Hospital to Home
, 2021 Aims: Transition Care Programs support older adults to return home post hospital admission. This study explored the experiences of older adults who identified therapy goals relating to out-of-home occupations.
Athan, V +9 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Cuerpos de mujer en el mundo laboral bilbaíno bajomedieval y moderno (s. XIV –XVI).
Nuevo mundo - Mundos Nuevos, 2008 Women’s labor was highly regulated in the ordinances and municipal records, and becomes a useful source to appreciate the level of feminine participation in the urban world of Bilbao in the late Middle Ages and in Early Modern period.
Ana María Rivera Medina
doaj +1 more source
The “Managing Fatigue” programme – Experiences shared by MS participants
Scandinavian Journal of Occupational Therapy, 2021 Background The “Managing Fatigue” (MF) programme can help people living with Multiple sclerosis (MS) manage fatigue in their everyday lives. The programme has been proven feasible with Swedish occupational therapists, but there is a lack of knowledge of ...
Anna Gillisdotter +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Ranking Research Priorities in Health, Safety and Environment (HSE)
Salāmat-i kār-i Īrān, 2020 Background and aims: The diversity of health, safety and environmental issues (HSE) and limitations of the resources hinders response to all the research needs in the field of HSE. HSE promotion and policy making require research based on the real needs
Ali Asghar Farshad +5 more
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Journal of Rehabilitation, 2020 Objective: Caring for individuals with multiple sclerosis (MS) can affect their caregivers’ occupational performance in various areas such as work, rest/sleep, and social participation. Part of the rehabilitation process is educating caregivers.
Mohammad Taghi Mohseni Takalu +4 more
doaj +1 more source