Results 81 to 90 of about 5,361,294 (297)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Prevalence of Post-traumatic Stress Disorder Symptoms among Road Traffic Accident Victims: A Cross-sectional Study from Gujarat, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Road Traffic Accidents (RTAs) can develop Post-Traumatic Stress Disorder (PTSD) due to emotional trauma, which significantly affects the quality of life. Despite satisfactory psychological recovery for many RTA victims, a notable percentage
Hetal Jitendrabhai Shah, Sapna Patel, Sandeep Patel   +2 more
doaj   +1 more source

Occurrence of ?whimper? singularities [PDF]

General Relativity and Gravitation, 1978
HOmogeneous space-times (i.e. those admitting a three-parameter group of isometries) are studied using the Newman Penrose formalism. It is found that solutions containing horizons depend on two fewer parameters than the most general solution, so that horizons and the associated whimper singularities are not stable features of homogeneous space-times ...
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

AI Text Generators and the Truth Paradigm: Considerations from a Phenomenological Perspective

Filozofia
NLP has opened a new level for artificial intelligence: the truth. But AI text generators do not tell the truth reliably. That creates the contradiction of a truth-seeking authority saying something untrue. The paradigm of truth seems to be under attack.
Kathrin Burghardt
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Integration of Multi-Omics Data Identifies the Role of the Selenium-Related Gene PNPO and Pre-exhausted CD127 CD8 T Cells in Laryngeal Carcinoma

Cancer Informatics
Objective: To elucidate mechanistic links among selenium measures, selenium-related genes, and immune traits in laryngeal carcinoma (LC) by integrating Mendelian randomization, bulk transcriptomic, and single-cell analyses.
Lin Xiang, Lin Chen, Cheng Gong, Yao Tang   +3 more
doaj   +1 more source

Solar Flare Occurrence Rate and Waiting Time Statistics

, 2012
We use Renewal Theory for the estimation and interpretation of the flare rate from the Geostationary Operational Environmental Satellite (GOES) soft X-ray flare catalogue. It is found, that in addition to the flare rate variability with the solar cycles,
Gorobets, Andrei, Messerotti, Mauro
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Ethical behavior profiles among nursing interns and their determinants: a latent profile analysis

BMC Medical Education
Objective Ethical practice is a core professional expectation in nursing, yet nursing interns may vary substantially in how they enact ethical principles during clinical placements.
Jia Qu, Pu Lin, Li Liu, Min Min, Yayun Song   +4 more
doaj   +1 more source