Results 61 to 70 of about 1,977,117 (265)

Integrating photovoice as an adjunct teaching modality in improving critical thinking disposition among Chinese nursing students in community health nursing: a mixed-methods study

BMC Nursing
Aims This study aimed to examine the effectiveness of using Photovoice as an adjunct teaching modality to enhance critical thinking dispositions among Chinese nursing students in a community health nursing course.
Yayun Song, Huan Yang, Mengjiao Zhou, Dongyi Zhang, Jia Qu   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

INJURY RISK FACTORS IN CHILDREN AND YOUTH IN PHYSICAL / SPORTS ACTIVITY

Annales Kinesiologiae, 2015
Purpose: The aim of the article is to define the injury risk factors in physical/sports activity and how they may correlate.  Methods: A systematic review of electronic databases MEDLINE, Google Scholar, ScienceDirect and Cinahl in May 2015 has ...
Marina Dobnik
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Prevalence of Post-traumatic Stress Disorder Symptoms among Road Traffic Accident Victims: A Cross-sectional Study from Gujarat, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Road Traffic Accidents (RTAs) can develop Post-Traumatic Stress Disorder (PTSD) due to emotional trauma, which significantly affects the quality of life. Despite satisfactory psychological recovery for many RTA victims, a notable percentage
Hetal Jitendrabhai Shah, Sapna Patel, Sandeep Patel   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

AI Text Generators and the Truth Paradigm: Considerations from a Phenomenological Perspective

Filozofia
NLP has opened a new level for artificial intelligence: the truth. But AI text generators do not tell the truth reliably. That creates the contradiction of a truth-seeking authority saying something untrue. The paradigm of truth seems to be under attack.
Kathrin Burghardt
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Integration of Multi-Omics Data Identifies the Role of the Selenium-Related Gene PNPO and Pre-exhausted CD127 CD8 T Cells in Laryngeal Carcinoma

Cancer Informatics
Objective: To elucidate mechanistic links among selenium measures, selenium-related genes, and immune traits in laryngeal carcinoma (LC) by integrating Mendelian randomization, bulk transcriptomic, and single-cell analyses.
Lin Xiang, Lin Chen, Cheng Gong, Yao Tang   +3 more
doaj   +1 more source