Results 71 to 80 of about 5,361,294 (297)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

Frontiers in Genetics
ObjectiveThis study aimed to identify early biomarkers associated with the progression from atherosclerosis (AS) to heart failure (HF) by integrating single-cell RNA sequencing (scRNA-seq) and bulk transcriptomic data, and to explore the potential ...
Lihua Ni, Huabo Li, Huabo Li, Juan Du, Juan Du, Ke Zhou, Ke Zhou, Fugui Zhang, Fugui Zhang, Liankai Wang, Liankai Wang   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Performance changes during and post-exercise in combined heat and hypoxia environments: a systematic review and network meta analysis

Journal of Translational Medicine
Background This study aims to compare exercise performance, as well as physiological, and psychological changes, when individuals exercise both during and after exposure to the heat environment (HEAT), the hypoxia environment (HYP), and the combined heat
Jianfeng Huang, Weiqing Huang, Wenxuan Yang, Jun Lei, Yuqing Wang, Xin Dong, Daiyu Zhu   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrating photovoice as an adjunct teaching modality in improving critical thinking disposition among Chinese nursing students in community health nursing: a mixed-methods study

BMC Nursing
Aims This study aimed to examine the effectiveness of using Photovoice as an adjunct teaching modality to enhance critical thinking dispositions among Chinese nursing students in a community health nursing course.
Yayun Song, Huan Yang, Mengjiao Zhou, Dongyi Zhang, Jia Qu   +4 more
doaj   +1 more source

INJURY RISK FACTORS IN CHILDREN AND YOUTH IN PHYSICAL / SPORTS ACTIVITY

Annales Kinesiologiae, 2015
Purpose: The aim of the article is to define the injury risk factors in physical/sports activity and how they may correlate.  Methods: A systematic review of electronic databases MEDLINE, Google Scholar, ScienceDirect and Cinahl in May 2015 has ...
Marina Dobnik
doaj   +1 more source

Occurrence of some Lejeuneaceae (Jungermanniophyta) in Bahia, Brazil [PDF]

, 2000
Five species of Lejeuneaceae, tribe Lejeuneae from state of Bahia, Brazil are described and illustrated.
Bastos, Cid José Passos, Bôas-Bastos, Silvana Brito Vilas   +1 more
core  

Quantum jumps induced by the center-of-mass motion of a trapped atom

, 2010
We theoretically study the occurrence of quantum jumps in the resonance fluorescence of a trapped atom. Here, the atom is laser cooled in a configuration of level such that the occurrence of a quantum jump is associated to a change of the vibrational ...
A. Aspect, A. Kreuter, A.S. Manka, B. Appasamy, B.R. Mollow, C. Cohen-Tannoudji, C. Schuck, D. Leibfried, D.J. Gauthier, E. Arimondo, G.C. Hegerfeldt, I. Dotsenko, J. Eschner, J. Eschner, J. Metz, J. Metz, J. Metz, J. Raab, J.C. Bergquist, J.I. Cirac, J.I. Cirac, K. Mølmer, L.M. Narducci, M. Bienert, M. Bienert, M. Bienert, M. Fleischhauer, M. Gatzke, M. Jakob, M. Lindberg, M.A.G. Martinez, M.B. Plenio, N. Bohr, N. Bohr, P. Zhou, S. Harris, S. Stenholm, S. Wallentowitz, S.A. Gardiner, T. Sauter, V. Bühner, W. Nagourney, W.M. Itano, Y. Stalgies   +43 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source