Results 71 to 80 of about 1,977,117 (265)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Ethical behavior profiles among nursing interns and their determinants: a latent profile analysis

BMC Medical Education
Objective Ethical practice is a core professional expectation in nursing, yet nursing interns may vary substantially in how they enact ethical principles during clinical placements.
Jia Qu, Pu Lin, Li Liu, Min Min, Yayun Song   +4 more
doaj   +1 more source

The Occurrence and Bioactivities of Amaryllidaceae Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review

Plants
The distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
G. David Lin, Pinky Vishwakarma, Paul N. Smith, Rachel W. Li   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Distribuição e frequência de aves aquáticas em habitats de lagos de um parque urbano em São Paulo, SP. Distribution and frequency of waterfowl in habitats of lakes of an urban park in São Paulo, SP. [PDF]

Revista do Instituto Florestal, 2013
Aves aquáticas destacam-se por ser uma importante ferramenta para verificar o grau de conservação e qualidade dos habitats, além da grande capacidade de algumas espécies em deslocar-se para escolha dos mesmos.
Renato Ferreira LEMOS; Vanessa SIMEI-MARTINS; Arlaine dos Santos FRANCISCO, Vanessa SIMEI-MARTINS, Arlaine dos Santos FRANCISCO   +2 more
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Occurrence of Aflatoxin M1 over Three Years in Raw Milk from Croatia: Exposure Assessment and Risk Characterization in Consumers of Different Ages and Genders

Foods
In this study, the frequency of aflatoxin M1 (AFM1) occurrence in raw milk was investigated across different seasons over a three-year period from 2022 to 2024 in Croatia. Risk assessment was conducted using estimated daily intake (EDI), hazard index (HI)
Nina Bilandžić, Ines Varga, Bruno Čalopek, Božica Solomun Kolanović, Ivana Varenina, Maja Đokić, Marija Sedak, Luka Cvetnić, Damir Pavliček, Ana Končurat   +9 more
doaj   +1 more source

Primeiro relato de Spalangia nigroaenea Curtis, 1839 (Hymenoptera: pteromalidae) em pupas de fannia pusio (Wiedemann, 1830) (Diptera: fanniidae) no Brasil First report of Spalangia nigroaenea Curtis, 1839 (Hymenoptera: Pteromalidae) in pupae of Fannia pusio (Wiedemann, 1830) (Diptera: Fanniidae) in Brazil

Ciência e Agrotecnologia, 2008
Relata-se a primeira ocorrência do parasitóide Spalangia nigroaenea Curtis, 1839 (Hymenoptera: Pteromalidae) em pupas de Fannia pusio (Wiedemann, 1830) (Diptera: Fanniidae), no Brasil. Pupas de F.
Carlos Henrique Marchiori, Vanessa Alves Alvarenga   +1 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Regulatory mechanisms of m6A RNA methylation in esophageal cancer: a comprehensive review

Frontiers in Genetics
Esophageal cancer is an aggressively malignant neoplasm characterized by a high mortality rate. Frequently diagnosed at an advanced stage, it presents challenges for optimal therapeutic intervention due to its non-specific symptoms, resulting in lost ...
Long Wen, Long Wen, Jiang Fu, Zixu Wang, Rangping Xie, Rangping Xie, Shengjie Tang, Li Yu, Haining Zhou, Haining Zhou, Haining Zhou, Haining Zhou   +11 more
doaj   +1 more source