Results 141 to 150 of about 45,241 (308)

Investigating the Role of Glutamate in Obsessive-Compulsive Disorder: Current Perspectives

open access: yesNeuropsychiatric Disease and Treatment, 2020
Sheshachala Karthik,* Lavanya P Sharma,* Janardhanan C Narayanaswamy OCD Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore 560029, India*These authors contributed equally to this ...
Karthik S, Sharma LP, Narayanaswamy JC
doaj  

GGOC‐AD: a mHealth tool to challenge obsessive‐compulsive related maladaptive beliefs in Spanish community adolescents: a randomized controlled trial

open access: yesChild and Adolescent Mental Health, EarlyView.
Background Obsessive‐compulsive related maladaptive beliefs play an essential role in the development and maintenance of obsessive‐compulsive disorder (OCD). Nevertheless, there is a lack of accessible and widespread strategies capable of challenging such beliefs in the youth general population.
Yuliya Saman   +9 more
wiley   +1 more source

Parental Views on Discipline and Parenting Practices Post‐Physical Punishment Ban in Wales

open access: yesChildren &Society, EarlyView.
ABSTRACT Child physical punishment was outlawed in Wales in March 2022. Previous research suggests that legislative changes prohibiting physical punishment can positively influence attitudes towards child discipline methods. This exploratory study investigated the impact of this legislative ban on Welsh parents' attitudes towards physical punishment ...
Lauren James   +1 more
wiley   +1 more source

Mental health difficulties in cerebral palsy: A qualitative study of young people's and parents' perspectives

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To explore the experiences of mental health difficulties and access to mental health support among young people with cerebral palsy (CP). Method We used a qualitative descriptive design. Participants were young people with CP aged 13 to 25 years and parents of children with CP (6–25 years).
Manjula Manikandan   +15 more
wiley   +1 more source

Sleep profiles in individuals with rare neurogenetic syndromes

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To characterize sleep profiles in individuals with neurogenetic disorders (NGDs) and examine the contribution of key clinical and psychiatric symptoms to these profiles. Method The parents of 248 individuals (aged 3–45 years) diagnosed with a range of NGDs, including PTEN hamartoma tumor syndrome (n = 111), SYNGAP1‐related intellectual disability ...
Isabella C. Reyes   +7 more
wiley   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid   +8 more
wiley   +1 more source

Influence of rubbing during etching on surface roughness and interfacial characteristics of intact enamel

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract Rubbing phosphoric acid during etching has been shown to improve surface roughness in prepared enamel. This study aimed to compare intact enamel's surface roughness and resin tag lengths after etching with and without rubbing. Extracted sound third molars were used for testing, mesially for conventional and distally for dynamic (rubbing ...
Moana Biedermann   +5 more
wiley   +1 more source

“I Self‐Protect to Avoid Child Protection”: Transgender Parents' Fears of Help‐Seeking and Social Service Systems

open access: yesFamily Relations, EarlyView.
ABSTRACT Objective This mixed‐methods study examined transgender (trans) parents' concerns about being targeted and reported to child protective services by schools, health care providers, neighbors, and family members. Background Trans people and parents specifically may be experiencing heightened fears about interfacing with sources of potential ...
Abbie E. Goldberg   +3 more
wiley   +1 more source

Ion binding sites and intermediate domain closure induced by D‐serine in the GluD1 ligand‐binding domain

open access: yesThe FEBS Journal, EarlyView.
GluD1 belongs to the ionotropic glutamate receptors and has important functions in the brain and brain diseases. We report the crystal structure of the GluD1 ligand‐binding domain with D‐serine and zinc ions. MD simulations supported promiscuous binding of cations and that chloride ions play a stabilizing role. Pro725 seems to hinder interlobe closure,
Flemming Steen Jørgensen   +4 more
wiley   +1 more source

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