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Urinary ochratoxin A and ochratoxin alpha in pregnant women

Food and Chemical Toxicology, 2012
This study determined exposure of pregnant women to ochratoxin A (OTA). Forty samples of first-void urine samples from Croatian women in the third trimester of pregnancy were analyzed for OTA and its major metabolite ochratoxin alpha (OTα). The subjects filled a short food frequency questionnaire (FFQ).
Bojan Šarkanj   +3 more
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Synthesis of analogues of ochratoxin A

Natural Product Research, 2012
Four analogues of ochratoxin A (OTA) differing for the aminoacidic moiety were synthesised using ochratoxin α (OTα) as the starting material. The condensation reaction between protected amino acids and OTα, carried out in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC • HCl) and N-hydroxybenzotriazole (HOBt) as ...
Plastina P.   +4 more
openaire   +5 more sources

Broad-specificity photoelectrochemical immunoassay for the simultaneous detection of ochratoxin A, ochratoxin B and ochratoxin C

Biosensors and Bioelectronics, 2018
A broad-specific photoelectrochemical (PEC) immunosensor was developed for the simultaneous detection of ochratoxin A, ochratoxin B and ochratoxin C (OTA, OTB, OTC) by using the direct growth of CdS nanorods on FTO as the photoelectrode and Au nanoflowers-modified glass carbon electrode (GCE) as the bioelectrode.
Weipeng Liu   +7 more
openaire   +3 more sources

Immunotoxic activity of ochratoxin A

Journal of Veterinary Pharmacology and Therapeutics, 2006
Ochratoxin A (OTA) is an immunosuppressant fungal compound, produced by toxigenic species ofAspergillusandPenicilliumfungi in a wide variety of climates and geographical regions. The contamination of food by this mycotoxin takes place primarily during preharvest periods. Almost all types of food can be contaminated.
Ernst Petzinger, L Al-Anati
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Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function

Mycotoxin Research, 2002
The effect of practically relevant mycotoxin concentrations on functions of immune cells was studied in in vitro experiments. Porcine mononuclear cells were exposed to a crudeAspergillus-ochraceus toxin containing OTA, a HPLC fraction identical with OTC derived from the crude toxin (RE2), as well as pure OTA and OTC in a concentration range from 0.46 ...
H. Rosner   +5 more
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OCHRATOXIN A IN TURKISH WINES

Journal of Food Biochemistry, 2005
In this research, 47 wine samples produced from 2001 to 2002 harvest period in four Turkish regions were analyzed for the presence of ochratoxin A (OTA). Based on the results, the OTA levels of red wines are generally higher than those of white and rose wines.
Vural, NİLÜFER   +3 more
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The fate of ochratoxin A in rats

Food and Cosmetics Toxicology, 1977
Abstract The fate of ochratoxin A was studied in rats given a single ip injection of 1 mg labelled with 14 C. Ochratoxin A reached its highest levels in serum (accounting for up to 90% of the 14 C dose), liver (4·5%) and kidney (4·4%) 30 min after the injection and then decreased gradually.
F.C. Chang, F.S. Chu
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Ochratoxins: A global perspective

Mycopathologia, 2006
Ochratoxins have been overshadowed by better-known mycotoxins, but they are gaining importance. Here we consider ochratoxins in the context of aflatoxins, which are better understood than ochratoxins on many levels. We review recent work on taxonomic distribution, contamination of commodities, biosynthesis, toxicity and regulatory aspects of ...
Paul Bayman, James L. Baker
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Synthesis of ochratoxins TA and TC, analogs of ochratoxins A and C

Experientia, 1974
Zwei Ochratoxinanaloge, Ochratoxin TA (OTA) und TC (OTC) wurden aus Ochratoxin-α chemisch synthetisiert indem Phenylalanin und sein Athylester im Molekul durch Tyrosin und Tyrosinathylester substituiert wurden. Der Huhnerembryonentest ergab, dass OTC etwas toxischer und OTA etwas weniger toxisch ist als Ochratoxin A (OA).
Ru-Dong Wei, F. S. Chu
openaire   +3 more sources

Ochratoxin A and Epigenetics

2017
Ochratoxin A is a thermoresistant mycotoxin produced by ubiquitous molds of Aspergillus and Penicillium genera. It contaminates foodstuffs and feedstuffs worldwide and therefore is of human and animal concern. Ochratoxin A induces oxidative stress, inflammation, and fibrosis, and is nephrotoxic, hepatotoxic, and neurotoxicin particularly in male ...
openaire   +3 more sources

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